Clopidogrel
別名: Plavix, Antiplaq, Clodian, Cloflow, Clopact, Clopivas, Clopod, Iscover, Iskimil, Nabratin, Noklot, Pleyar, Troken
- **Purpose**: This medication helps prevent life-threatening blood clots. - **Administration**: May be given with or without food. If vomiting occurs, give with food. - **Feline Tip**: This medication is extremely bitter. Do not crush it or let it dissolve in your cat's mouth, as it will cause severe drooling. Hiding the pill fragment inside an empty gelatin capsule or a pill pocket is highly recommended. - **Bleeding Risk**: Because it stops blood from clotting, watch for unusual bruising, bleeding from the gums, nosebleeds, or black, tarry stools. Report any of these signs to your veterinarian immediately. - **Appetite**: Report any lack of appetite or persistent vomiting to your veterinarian.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- As an anti-platelet agent
- Thromboprophylaxis
- To prevent thrombus formation
- To prevent thrombus formation (combination therapy)
- To prevent thrombus formation
- Thromboprophylaxis
給藥方式
可能的副作用
- Vomiting
- Anorexia
- Bleeding/hemorrhage
- Diarrhea
- Rashes
- Thrombotic thrombocytopenic purpura (TTP) - rare in humans
注意事項與禁忌
- Active pathologic bleeding
- Known hypersensitivity to the drug
- > **Bleeding Risk**: Use with caution in patients at risk for bleeding from trauma, surgery, or other pathological conditions. > **Pregnancy/Nursing**: FDA Category B in humans. Probably safe in nursing veterinary patients, but weigh potential risks to offspring or use a milk replacer.
藥物相互作用
- Aspirin: Increased risk for bleeding; however, many patients take both medications intentionally for dual antiplatelet therapy.
- Heparin / Low Molecular Weight Heparins (LMWH): Clopidogrel appears safe to use concurrently with heparin.
- NSAIDs: Increased risk for bleeding; clopidogrel may interfere with NSAID metabolism.
- Phenytoin: Clopidogrel may interfere with phenytoin metabolism.
- Proton Pump Inhibitors (e.g., omeprazole): May decrease the efficacy of clopidogrel by inhibiting CYP2C19, the enzyme needed to convert clopidogrel to its active metabolite.
- Torsemide: Clopidogrel may interfere with torsemide metabolism.
- Warfarin: Increased risk for bleeding; clopidogrel may interfere with warfarin metabolism.
- Anticoagulants: High risk of bleeding complications
常見問題
Clopidogrel用於寵物有甚麼用途？
- **Purpose**: This medication helps prevent life-threatening blood clots. - **Administration**: May be given with or without food. If vomiting occurs, give with food. - **Feline Tip**: This medication is extremely bitter. Do not crush it or let it dissolve in your cat's mouth, as it will cause severe drooling. Hiding the pill fragment inside an empty gelatin capsule or a pill pocket is highly recommended. - **Bleeding Risk**: Because it stops blood from clotting, watch for unusual bruising, bleeding from the gums, nosebleeds, or black, tarry stools. Report any of these signs to your veterinarian immediately. - **Appetite**: Report any lack of appetite or persistent vomiting to your veterinarian.
Clopidogrel對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。