Cefazolin
別名: Ancef, Kefzol, Zolicef
Cefazolin is an injectable antibiotic that is typically administered by your veterinarian in a clinic or hospital setting, most commonly to prevent infection during surgery or to treat severe systemic infections. > **Important Note:** Because this medication is given via injection (intravenously or intramuscularly), you will not need to administer it at home. * **Allergic Reactions:** While rare, if your pet exhibits signs of an allergic reaction after returning home (such as facial swelling, hives, or difficulty breathing), contact your veterinarian immediately. * **Injection Site:** Your pet may experience mild soreness at the injection site. If you notice severe swelling, redness, or pain, let your veterinary team know.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Gram-positive infections
- Gram-negative infections
- Surgical prophylaxis (Orthopedic procedures)
- Surgical prophylaxis (Soft tissue surgery)
- Sepsis
- Systemic infections
- Susceptible infections
- Infections in neonates
- Susceptible infections
- Susceptible infections
- Susceptible infections (Foals)
- Susceptible infections (Neonatal foals)
- Surgical prophylaxis (Orthopedic procedures)
- Surgical prophylaxis (Soft tissue surgery)
給藥方式
可能的副作用
- Hypersensitivity reactions (rashes, fever, eosinophilia, anaphylaxis)
- Pain at the IM injection site
- Sterile abscesses or local tissue reactions (rare)
- Thrombophlebitis (following IV administration)
- Nephrotoxicity (minimal risk at clinical doses)
- Neurotoxicity or seizures (associated with very high IV doses)
- GI flora disruption (in nursing neonates)
注意事項與禁忌
- Patients with a known history of hypersensitivity to cephalosporins
- Use cautiously in patients with documented hypersensitivity to other beta-lactam antibiotics (e.g., penicillins, carbapenems) due to the potential for cross-reactivity. Dosage adjustments may be necessary in patients with severe renal failure, as the drug is primarily excreted unchanged by the kidneys. Safe use during pregnancy has not been firmly established (FDA Category B), though teratogenic effects have not been documented; use only when benefits outweigh risks. Cefazolin is distributed into milk and may alter neonatal gut flora in nursing dams.
藥物相互作用
- Aminoglycosides: Potential for additive nephrotoxicity; use concurrently with caution.
- Amphotericin B: Potential for additive nephrotoxicity; use concurrently with caution.
- Probenecid: Competitively blocks the renal tubular secretion of cefazolin, thereby increasing serum levels and prolonging the elimination half-life.
常見問題
Cefazolin用於寵物有甚麼用途？
Cefazolin is an injectable antibiotic that is typically administered by your veterinarian in a clinic or hospital setting, most commonly to prevent infection during surgery or to treat severe systemic infections. > **Important Note:** Because this medication is given via injection (intravenously or intramuscularly), you will not need to administer it at home. * **Allergic Reactions:** While rare, if your pet exhibits signs of an allergic reaction after returning home (such as facial swelling, hives, or difficulty breathing), contact your veterinarian immediately. * **Injection Site:** Your pet may experience mild soreness at the injection site. If you notice severe swelling, redness, or pain, let your veterinary team know.
Cefazolin對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。