貝那普利
別名: Fortekor, Lotensin, Benace, Boncordin, Briem, Cibace, Cibacen, Cibacene, Labopal, Lotrel, Tensanil, Zinadril, Cardalis, Nelio, Benefortin, Benazecare
藥物類別: Angiotensin Converting Enzyme (ACE) Inhibitor
- **請勿自行停藥**：未經獸醫師同意，請勿突然停止給藥或減少劑量。 - **觀察副作用**：如果寵物出現持續或嚴重的嘔吐、腹瀉，或病情惡化（如嗜睡、虛弱、昏厥），請立即聯繫獸醫師。 - **給藥方式**：可與食物一起或空腹餵食。請確保寵物隨時有充足的新鮮飲水。 - **定期回診**：使用此藥物期間，定期回診讓獸醫師監測寵物的血壓與腎功能是非常重要的。
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- Adjunctive treatment of heart failure
- Adjunctive treatment of heart failure
- Adjunctive treatment of hypertension and/or proteinuria (first step)
- Adjunctive treatment of hypertension and/or proteinuria
- Hypertension associated with protein-losing renal disease
- Proteinuria, hypertension
- Heart failure
- Adjunctive treatment of hypertension/proteinuria
- Adjunctive treatment of heart failure
- CHF or hypertension
- Adjunctive treatment of hypertension
- Adjunctive treatment of hypertension
- Adjunctive treatment of hypertension
- Proteinuria, hypertension associated with chronic kidney disease
- Proteinuria, hypertension
- 2nd step drug for hypertension
- Chronic renal insufficiency (Management of proteinuria)
- Adjunctive therapy in heart failure
給藥方式
PO
可能的副作用
- Anorexia
- Vomiting
- Diarrhea
- Hypotension
- Renal dysfunction (worsening azotemia)
- Hyperkalemia
注意事項與禁忌
- Known hypersensitivity to ACE inhibitors
- > **Important Warnings:** * Use with caution in patients with **hyponatremia** or sodium depletion, coronary or cerebrovascular insufficiency, preexisting hematologic abnormalities, or collagen vascular diseases (e.g., SLE). * Patients with severe congestive heart failure (CHF) should be monitored very closely upon initiation of therapy due to the risk of profound hypotension. * ACE inhibitors can potentially worsen preexisting **azotemia**. It is recommended to use a lower starting dose and closely monitor BUN and creatinine. * **Pregnancy:** Mildly fetotoxic at high dosages. Use during pregnancy only when potential benefits outweigh the risks to the offspring (FDA Category C in first trimester, Category D in second/third trimesters).
藥物相互作用
- Aspirin: May potentially negate the decrease in systemic vascular resistance induced by ACE inhibitors (though low-dose aspirin may not significantly affect hemodynamics).
- Antidiabetic Agents (insulin, oral agents): Possible increased risk for hypoglycemia; enhanced monitoring recommended.
- Diuretics (e.g., furosemide, hydrochlorothiazide): Potential for increased hypotensive effects. Reducing furosemide doses by 25-50% is often recommended when initiating ACE inhibitors for heart failure.
- Potassium-Sparing Diuretics (e.g., spironolactone, triamterene): Increased risk of hyperkalemia; enhanced monitoring of serum potassium is required.
- Lithium: Possible increased serum lithium levels; increased monitoring required.
- Potassium Supplements: Increased risk for hyperkalemia.
- Spironolactone: Potential for hyperkalemia due to additive potassium-sparing effects, though concurrent use is generally safe in practice.
- NSAIDs: Increased risk of nephrotoxicity and decreased clinical efficacy of benazepril.
- Diuretics (e.g., Furosemide): Increased risk of hypotension and prerenal azotemia.
- Vasodilators (e.g., Amlodipine, Anesthetic agents): Additive hypotensive effects.
- Beta-blockers: Increased risk of hypotension due to negative inotropic effects.
常見問題
貝那普利用於寵物有甚麼用途？
- 請勿自行停藥：未經獸醫師同意，請勿突然停止給藥或減少劑量。 - 觀察副作用：如果寵物出現持續或嚴重的嘔吐、腹瀉，或病情惡化（如嗜睡、虛弱、昏厥），請立即聯繫獸醫師。 - 給藥方式：可與食物一起或空腹餵食。請確保寵物隨時有充足的新鮮飲水。 - 定期回診：使用此藥物期間，定期回診讓獸醫師監測寵物的血壓與腎功能是非常重要的。
貝那普利對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。