Benazepril
別名: Fortekor, Lotensin, Benace, Boncordin, Briem, Cibace, Cibacen, Cibacene, Labopal, Lotrel, Tensanil, Zinadril, Cardalis, Nelio, Benefortin, Benazecare
- **Do Not Abruptly Stop:** Do not abruptly stop or reduce therapy without your veterinarian's approval. - **Monitor for Side Effects:** Contact your veterinarian immediately if vomiting or diarrhea persists or is severe, or if your animal's condition deteriorates (e.g., lethargy, weakness, fainting). - **Administration:** Can be given with or without food. Ensure your pet always has access to fresh drinking water. - **Follow-up:** Regular veterinary visits are crucial to monitor your pet's blood pressure and kidney function while on this medication.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Adjunctive treatment of heart failure
- Adjunctive treatment of heart failure
- Adjunctive treatment of hypertension and/or proteinuria (first step)
- Adjunctive treatment of hypertension and/or proteinuria
- Hypertension associated with protein-losing renal disease
- Proteinuria, hypertension
- Heart failure
- Adjunctive treatment of hypertension/proteinuria
- Adjunctive treatment of heart failure
- CHF or hypertension
- Adjunctive treatment of hypertension
- Adjunctive treatment of hypertension
- Adjunctive treatment of hypertension
給藥方式
可能的副作用
- Anorexia
- Vomiting
- Diarrhea
- Hypotension
- Renal dysfunction (worsening azotemia)
- Hyperkalemia
注意事項與禁忌
- Known hypersensitivity to ACE inhibitors
- > **Important Warnings:** * Use with caution in patients with **hyponatremia** or sodium depletion, coronary or cerebrovascular insufficiency, preexisting hematologic abnormalities, or collagen vascular diseases (e.g., SLE). * Patients with severe congestive heart failure (CHF) should be monitored very closely upon initiation of therapy due to the risk of profound hypotension. * ACE inhibitors can potentially worsen preexisting **azotemia**. It is recommended to use a lower starting dose and closely monitor BUN and creatinine. * **Pregnancy:** Mildly fetotoxic at high dosages. Use during pregnancy only when potential benefits outweigh the risks to the offspring (FDA Category C in first trimester, Category D in second/third trimesters).
藥物相互作用
- Aspirin: May potentially negate the decrease in systemic vascular resistance induced by ACE inhibitors (though low-dose aspirin may not significantly affect hemodynamics).
- Antidiabetic Agents (insulin, oral agents): Possible increased risk for hypoglycemia; enhanced monitoring recommended.
- Diuretics (e.g., furosemide, hydrochlorothiazide): Potential for increased hypotensive effects. Reducing furosemide doses by 25-50% is often recommended when initiating ACE inhibitors for heart failure.
- Potassium-Sparing Diuretics (e.g., spironolactone, triamterene): Increased risk of hyperkalemia; enhanced monitoring of serum potassium is required.
- Lithium: Possible increased serum lithium levels; increased monitoring required.
- Potassium Supplements: Increased risk for hyperkalemia.
- Spironolactone: Potential for hyperkalemia due to additive potassium-sparing effects, though concurrent use is generally safe in practice.
- NSAIDs: Increased risk of nephrotoxicity and decreased clinical efficacy of benazepril.
- Diuretics (e.g., Furosemide): Increased risk of hypotension and prerenal azotemia.
常見問題
Benazepril用於寵物有甚麼用途？
- **Do Not Abruptly Stop:** Do not abruptly stop or reduce therapy without your veterinarian's approval. - **Monitor for Side Effects:** Contact your veterinarian immediately if vomiting or diarrhea persists or is severe, or if your animal's condition deteriorates (e.g., lethargy, weakness, fainting). - **Administration:** Can be given with or without food. Ensure your pet always has access to fresh drinking water. - **Follow-up:** Regular veterinary visits are crucial to monitor your pet's blood pressure and kidney function while on this medication.
Benazepril對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。