Acetylcysteine
別名: Mucomyst, Acetadote, NAC, ACC, Ilube, Parvolex, Fluimucil
> **Emergency Use:** Acetylcysteine is most commonly used in emergency, clinically supervised settings to treat life-threatening poisonings (such as Tylenol/acetaminophen ingestion). * **Taste and Odor:** The oral liquid formulation has a very strong, unpleasant odor resembling rotten eggs (sulfur) and tastes very bad. Your pet will likely resist taking it. In the hospital, it is often given through a feeding tube or mixed with strong flavorings to ensure the full dose is received. * **Side Effects:** The most common side effect is nausea or vomiting. If your pet vomits shortly after receiving an oral dose, contact your veterinarian immediately, as the dose may need to be repeated. * **Monitoring:** Your pet will require close monitoring, including frequent blood tests, to ensure the liver is recovering and the toxin is being cleared from the body.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Acetaminophen toxicity
- Acetaminophen toxicity
- Acetaminophen toxicity
- Phenol toxicity
- Hepatotoxicity secondary to xylitol poisoning
- Degenerative myelopathy (anecdotal)
- Mucolytic
- Paracetamol poisoning
- KCS
- Acetaminophen toxicity
- Phenol toxicity
- Adjunctive treatment of hepatic lipidosis
- Mucolytic
- Paracetamol poisoning
給藥方式
可能的副作用
- Nausea and vomiting (especially with oral administration due to poor palatability)
- Urticaria (rare)
- Bronchospasm, chest tightness, and bronchial/tracheal irritation (when inhaled)
- Blood pressure changes and allergic reactions (reported with IV boluses in humans)
注意事項與禁忌
- Hypersensitivity to the drug (specifically for pulmonary indications)
- Use with caution in animals with pre-existing bronchospastic diseases (e.g., feline asthma) when administering via the pulmonary route, as it may trigger bronchospasm. Oral administration can be challenging due to the extremely foul taste and odor (sulfur/rotten eggs); administration via a gastric or duodenal tube is often necessary. If using the inhalation solution for intravenous administration, it is highly recommended to use a 0.2-micron in-line filter. Use caution in nursing dams as it is unknown if the drug enters milk.
藥物相互作用
- Activated Charcoal: May adsorb orally administered acetylcysteine, potentially reducing its systemic absorption and efficacy. A 2-3 hour wait between charcoal and oral acetylcysteine is recommended, or acetylcysteine should be given intravenously.
常見問題
Acetylcysteine用於寵物有甚麼用途？
> **Emergency Use:** Acetylcysteine is most commonly used in emergency, clinically supervised settings to treat life-threatening poisonings (such as Tylenol/acetaminophen ingestion). * **Taste and Odor:** The oral liquid formulation has a very strong, unpleasant odor resembling rotten eggs (sulfur) and tastes very bad. Your pet will likely resist taking it. In the hospital, it is often given through a feeding tube or mixed with strong flavorings to ensure the full dose is received. * **Side Effects:** The most common side effect is nausea or vomiting. If your pet vomits shortly after receiving an oral dose, contact your veterinarian immediately, as the dose may need to be repeated. * **Monitoring:** Your pet will require close monitoring, including frequent blood tests, to ensure the liver is recovering and the toxin is being cleared from the body.
Acetylcysteine對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。