Selamectin
Also known as: Revolution, Selehold, Stronghold, Stronghold Plus
> **Important Application Instructions:** * Apply directly to the skin at the base of the neck in front of the shoulder blades. * **Do not massage** the liquid into the skin. * **Do not apply** if the pet's hair coat is wet. * Wait at least **two hours** after applying before bathing your pet or allowing them to swim. **Safety Warnings:** * Avoid contact with the application site until it is completely dry. * Avoid getting the product on your own skin; if contact occurs, wash off immediately with soap and water. * **Flammable:** Keep the product away from open flames or heat sources.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
What it is used for
- Heartworm prevention, flea control, ear mites, hookworms, roundworms
- Notoedric (face/head) mange (Notoedres cati)
- Biting lice
- Flea treatment/prevention, heartworm prevention, ear mites, biting lice, roundworms, hookworms
- Heartworm prevention
- Flea treatment/prevention, heartworm prevention (Off-label / specific regional labels)
- Ear mites (P. cunuculi) in rabbits
- Mites and fleas (Off-label)
- Prophylaxis and treatment of dirofilariasis, flea control, ticks, ear mites, sarcoptes
- Nasal mites (Pneumonyssoides caninum)
- Cheyletiellosis
- Biting lice
How it is given
Possible side effects
- Transient localized alopecia at application site (rare)
- Mild, transient gastrointestinal signs (vomiting, diarrhea) if ingested
- Transient local alopecia at the application site
- Application site irritation or pruritus
- Rarely: vomiting, diarrhea, lethargy, or anorexia
- Rarely: neurological signs (tremors, ataxia) in highly sensitive individuals
Cautions & contraindications
- Application to broken skin
- Application to wet hair coats
- Use in severely debilitated or underweight animals (relative)
- Puppies and kittens under 6 weeks of age
- Sick, debilitated, or severely underweight animals
- Known hypersensitivity to the active substance or excipients
- Do not massage into skin. Do not apply if hair coat is wet. Because the product contains alcohol, do not apply to broken skin. The product is flammable; keep away from flame or other igniters.
Drug interactions
- Other macrocyclic lactones (e.g., ivermectin, milbemycin): Potential for additive toxicity, though selamectin has a high margin of safety.
- P-glycoprotein inhibitors (e.g., ketoconazole, cyclosporine): May theoretically increase systemic absorption and CNS penetration, increasing the risk of toxicity.
Frequently asked questions
What is Selamectin used for in pets?
> **Important Application Instructions:** * Apply directly to the skin at the base of the neck in front of the shoulder blades. * **Do not massage** the liquid into the skin. * **Do not apply** if the pet's hair coat is wet. * Wait at least **two hours** after applying before bathing your pet or allowing them to swim. **Safety Warnings:** * Avoid contact with the application site until it is completely dry. * Avoid getting the product on your own skin; if contact occurs, wash off immediately with soap and water. * **Flammable:** Keep the product away from open flames or heat sources.
Is Selamectin safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
This article is for general education and is not a substitute for professional veterinary advice. If your pet is unwell, please consult a veterinarian.
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