酚苄明
別名: Dibenzyline, Dibenyline
藥物類別: Alpha-Adrenergic Blocker
酚苄明通常用於放鬆泌尿道肌肉以幫助您的寵物更順暢地排尿，或用於控制與某些腎上腺腫瘤相關的高血壓。 - **需要耐心**：可能需要一週或更長時間才能看到對寵物排尿的完全效果。除非獸醫指示，否則請勿提早停藥。 - **隨餐服用**：將此藥物與食物一起餵食有助於減少腸胃不適（噁心或嘔吐）。 - **注意低血壓**：因為這種藥物會放鬆血管，可能會導致血壓下降。如果您的寵物出現虛弱、頭暈或在站立後倒下，請立即聯繫您的獸醫。 - **忘記服藥**：如果您忘記餵藥，請在想起時盡快補餵，但絕對不要一次餵食兩劑。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- Functional urethral obstruction
- Functional urethral obstruction
- Functional urethral obstruction
- Short-term treatment of hypertension
- Short-term treatment of hypertension
- Short-term treatment of hypertension
- Decrease urethral sphincter tone in bladder paresis
- Adjunctive treatment of laminitis (developmental phase)
- Treatment of profuse, watery diarrhea
- Functional urethral obstruction
- Functional urethral obstruction
- Functional urethral obstruction
- Functional urethral obstruction
- Hypertension associated with pheochromocytoma (pre-surgical)
- Hypertension associated with pheochromocytoma (medical management)
- Adjunctive treatment of endotoxicosis
給藥方式
POIV
可能的副作用
- Hypotension (postural/orthostatic)
- Hypertension (rebound)
- Miosis
- Increased intraocular pressure
- Tachycardia (reflex)
- Sodium retention
- Inhibition of ejaculation
- Nasal congestion
- Weakness or dizziness
- Gastrointestinal effects (nausea, vomiting)
- Constipation (specifically noted in horses)
- Hypotension
- Tachycardia
注意事項與禁忌
- Conditions where hypotension is undesirable (e.g., shock, unless fluid replacement is adequate)
- Horses with clinical signs of colic
- Glaucoma (relative contraindication)
- Diabetes mellitus (relative contraindication)
- Use with extreme caution in patients with **congestive heart failure (CHF)** or other heart disease, as drug-induced tachycardia can occur. Use cautiously in patients with renal damage or cerebral/coronary arteriosclerosis. **Pregnancy**: FDA Category C. Animal studies (guinea pigs) have shown abnormalities in the closure of the patent ductus. Use only if benefits outweigh risks.
藥物相互作用
- Epinephrine: Epinephrine reversal: If used with drugs that have both alpha- and beta-adrenergic effects, increased hypotension, vasodilation, or tachycardia may result due to unopposed beta effects.
- Phenylephrine: Phenoxybenzamine will antagonize the effects of alpha-adrenergic sympathomimetic agents.
- Reserpine: Phenoxybenzamine can antagonize the hypothermic effects of reserpine.
- Beta-blockers: Increased risk of first dose hypotensive effect; if used for phaeochromocytoma, beta-blockers must only be started after alpha blockade is in place to avoid hypertensive crisis.
- Diuretics: Increased risk of first dose hypotensive effect.
- Alpha-adrenergic sympathomimetics (e.g., phenylephrine): Phenoxybenzamine will antagonize the effects of these agents.
常見問題
酚苄明用於寵物有什麼用途？
酚苄明通常用於放鬆泌尿道肌肉以幫助您的寵物更順暢地排尿，或用於控制與某些腎上腺腫瘤相關的高血壓。 - 需要耐心：可能需要一週或更長時間才能看到對寵物排尿的完全效果。除非獸醫指示，否則請勿提早停藥。 - 隨餐服用：將此藥物與食物一起餵食有助於減少腸胃不適（噁心或嘔吐）。 - 注意低血壓：因為這種藥物會放鬆血管，可能會導致血壓下降。如果您的寵物出現虛弱、頭暈或在站立後倒下，請立即聯繫您的獸醫。 - 忘記服藥：如果您忘記餵藥，請在想起時盡快補餵，但絕對不要一次餵食兩劑。
酚苄明對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。