依替膦酸二鈉
別名: Didronel, Anfozan, Bonemass, Didronate, Difosfen, Diphos, Dralen, Dronate-OS, Etidrate, Etidron, Etiplus, Feminoflex, Ostedron, Osteodidronel, Osteum, Ostogene, Ostopor, Somaflex, Sviroxit
藥物類別: Oral Bisphosphonate Bone Resorption Inhibitor
> **重要給藥提示**:此藥物必須在**空腹**時給予,以確保適當吸收。食物(尤其是乳製品)會阻礙藥物進入寵物體內。 * **注意副作用**:如果您的寵物出現食慾不振、嘔吐或腹瀉,請立即聯繫您的獸醫師。 * **骨骼健康**:在極少數情況下,長期使用會影響骨骼強度。請觀察寵物是否有骨痛或跛行的跡象。 * 請勿在服用此藥物前後2小時內給予制酸劑或礦物質補充劑(如鈣或鐵)。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- For severe hypercalcemia associated with neoplastic disease
- For severe hypercalcemia associated with neoplastic disease
給藥方式
PO
可能的副作用
- Diarrhea
- Nausea (with higher oral doses)
- Bone pain/tenderness
- Increases in serum creatinine
- 'Frozen bone' syndrome in dogs (weakened bones and fractures due to inhibited bone remodeling)
注意事項與禁忌
- Severe renal function impairment (serum creatinine >5 mg/dL)
- Risk vs. benefit should be carefully considered in patients with **bone fractures** (delays healing), **enterocolitis** (higher risk of diarrhea), **cardiac failure** (especially with parenteral etidronate as patients may not tolerate the extra fluid load), or those with **moderate renal function impairment** (serum creatinines 2.5-5 mg/dL). > **Warning**: Do not confuse etidronate with etretinate or etomidate. Safety during pregnancy has not been established (FDA Category C). It is unknown if the drug enters milk.
藥物相互作用
- Antacids, dairy products, mineral supplements (iron, magnesium, calcium, aluminum): Absorption of oral etidronate may be inhibited; separate etidronate doses from these substances by at least two hours.
常見問題
依替膦酸二鈉用於寵物有什麼用途?
> **重要給藥提示**:此藥物必須在**空腹**時給予,以確保適當吸收。食物(尤其是乳製品)會阻礙藥物進入寵物體內。 * **注意副作用**:如果您的寵物出現食慾不振、嘔吐或腹瀉,請立即聯繫您的獸醫師。 * **骨骼健康**:在極少數情況下,長期使用會影響骨骼強度。請觀察寵物是否有骨痛或跛行的跡象。 * 請勿在服用此藥物前後2小時內給予制酸劑或礦物質補充劑(如鈣或鐵)。
依替膦酸二鈉對我的寵物安全嗎?
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育,不能取代專業獸醫意見。如寵物身體不適,請諮詢獸醫。