Sucralfate
別名: Carafate, Antepsin
- **Administration Timing:** To maximize the benefit of this medication, give it on an **empty stomach** (at least 1 hour before feeding or 2 hours after) and at bedtime, unless otherwise instructed by your veterinarian. - **Consistency:** Clinical signs of stomach upset or ulcers may reoccur if dosages are missed. Administer exactly as prescribed. - **Separating Medications:** Sucralfate can block the absorption of many other drugs. If your pet is taking other medications, give them at least 2 hours apart from the sucralfate. - **Administration Tip:** If you are given tablets, your veterinarian may instruct you to dissolve the tablet in a small amount of warm water to create a "slurry" before giving it via syringe. This liquid form coats the esophagus and stomach much better than a solid tablet. - **Side Effects:** This medication is generally very safe. The most common side effect is mild constipation. Contact your vet if your pet strains to defecate or if vomiting worsens.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- General dosing
- Empirical dosage
- For gastric ulcers, esophagitis
- General dosing
- For adjunctive treatment (used with acid suppressive drugs) for preventing stress-induced ulcers in foals
- For treating equine gastric ulcer syndrome
- Right dorsal colitis (colonic ulcers)
- For esophagitis
- General dosing
- Severe GI blood loss
- For eliminating Helicobacter gastritis infections
- Severe hematemesis and anemia
- For gastric ulcers, esophagitis
給藥方式
可能的副作用
- Constipation (most common in dogs and humans)
- Vomiting (reported primarily in cats)
- Constipation (most common)
- Hypophosphatemia (rare, with prolonged use)
注意事項與禁忌
- No absolute contraindications
- Use with caution in patients with decreased gastrointestinal transit times (e.g., megacolon, ileus) due to the risk of constipation
- Known hypersensitivity to sucralfate
- There are no known absolute contraindications to the use of sucralfate. * **GI Motility:** Because it may cause constipation, it should be used with caution in animals where decreased intestinal transit times might be deleterious. * **Pregnancy & Nursing:** FDA Category B in humans. Categorized as Class A (Probably safe) in dogs and cats. It is unknown if it is excreted in milk, but due to minimal systemic absorption, it is unlikely to be of concern in nursing animals. * **Timing of Administration:** Because it requires an acidic environment to activate, it should ideally be given *before* acid-suppressing drugs (like H2 blockers or PPIs), typically separated by 30-60 minutes.
藥物相互作用
- Azithromycin: Decreased oral absorption; separate dosing by at least 2 hours
- Ciprofloxacin / Enrofloxacin (and other oral fluoroquinolones): Decreased oral absorption; separate dosing by at least 2 hours
- Diclofenac: Decreased oral absorption; separate dosing by at least 2 hours
- Digoxin: Decreased oral absorption; separate dosing by at least 2 hours
- Doxycycline: Decreased oral absorption; separate dosing by at least 2 hours
- Erythromycin: Decreased oral absorption; separate dosing by at least 2 hours
- Ketoconazole: Decreased oral absorption; separate dosing by at least 2 hours
- Levothyroxine: Decreased oral absorption; separate dosing by at least 2 hours
- Penicillamine: Decreased oral absorption; separate dosing by at least 2 hours
- Tetracycline: Decreased oral absorption; separate dosing by at least 2 hours
- Theophylline: Decreased oral absorption; separate dosing by at least 2 hours
常見問題
Sucralfate用於寵物有甚麼用途？
- **Administration Timing:** To maximize the benefit of this medication, give it on an **empty stomach** (at least 1 hour before feeding or 2 hours after) and at bedtime, unless otherwise instructed by your veterinarian. - **Consistency:** Clinical signs of stomach upset or ulcers may reoccur if dosages are missed. Administer exactly as prescribed. - **Separating Medications:** Sucralfate can block the absorption of many other drugs. If your pet is taking other medications, give them at least 2 hours apart from the sucralfate. - **Administration Tip:** If you are given tablets, your veterinarian may instruct you to dissolve the tablet in a small amount of warm water to create a "slurry" before giving it via syringe. This liquid form coats the esophagus and stomach much better than a solid tablet. - **Side Effects:** This medication is generally very safe. The most common side effect is mild constipation. Contact your vet if your pet strains to defecate or if vomiting worsens.
Sucralfate對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。