左乙拉西坦
別名: Keppra, Keppra XR, Desitrend
藥物類別: Anticonvulsant
* **嚴格的給藥時間**：此藥物必須完全依照醫囑給藥，通常為**每8小時（一天三次）**。漏藥可能導致癲癇突破性發作。 * **副作用**：初期您的寵物可能會出現嗜睡、精神不佳或食慾下降。這些副作用通常會隨著寵物適應藥物而改善。 * **癲癇日誌**：請詳細記錄任何癲癇發作的情況（日期、時間、持續時間和嚴重程度），以協助獸醫師調整劑量。 > **切勿自行停藥**：突然停止使用此藥物可能引發嚴重且危及生命的癲癇發作。在更改劑量前，請務必諮詢您的獸醫師。
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- As an add-on to phenobarbital treatment for epilepsy
- As an adjunct to phenobarbital in suspected idiopathic epilepsy
- As an add-on treatment for epilepsy in dogs refractory to phenobarbital and bromides
- As an add-on treatment for epilepsy in dogs refractory to phenobarbital and/or bromides
- Seizure management
- Seizure management
- Seizure management
- Single-dose pharmacokinetic study
- For status epilepticus
給藥方式
POIVRectal
可能的副作用
- Sedation (most common in dogs)
- Lethargy (most common in cats)
- Decreased appetite (most common in cats)
- Behavior changes
- Gastrointestinal effects
- Sedation (dogs)
- Ataxia (dogs)
- Reduced appetite (cats)
- Hypersalivation (cats)
- Lethargy (cats)
注意事項與禁忌
- Hypersensitivity to levetiracetam or any of its components
- Severe renal disease
- > **Renal Impairment:** Clearance is primarily renal (glomerular filtration and active tubular secretion). Dosage amounts or intervals must be adjusted in patients with decreased creatinine clearance. * **Pregnancy/Nursing:** FDA Category C. High doses in animal models showed embryofetal mortality and minor skeletal abnormalities. Excreted in maternal milk; use with caution in nursing patients. * **Withdrawal:** Abrupt discontinuation may precipitate withdrawal seizures; taper slowly if discontinuing.
藥物相互作用
- NSAIDs (naproxen, ketorolac): May increase the risk for seizures (reported in humans; veterinary significance unclear).
- Phenobarbital: Significantly increases levetiracetam clearance and reduces its half-life in dogs (from 3.43 hrs to 1.73 hrs); dosage adjustments may be required.
常見問題
左乙拉西坦用於寵物有甚麼用途？
• 嚴格的給藥時間：此藥物必須完全依照醫囑給藥，通常為每8小時（一天三次）。漏藥可能導致癲癇突破性發作。 • 副作用：初期您的寵物可能會出現嗜睡、精神不佳或食慾下降。這些副作用通常會隨著寵物適應藥物而改善。 • 癲癇日誌：請詳細記錄任何癲癇發作的情況（日期、時間、持續時間和嚴重程度），以協助獸醫師調整劑量。 > 切勿自行停藥：突然停止使用此藥物可能引發嚴重且危及生命的癲癇發作。在更改劑量前，請務必諮詢您的獸醫師。
左乙拉西坦對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。