Glycopyrrolate
別名: Robinul, Robinul-V, Robinul Forte
- **Parenteral administration** is best performed by professional staff in a clinical setting where adequate cardiac monitoring is available. - If your pet is receiving **glycopyrrolate tablets** at home, allow free access to water and encourage drinking, as dry mouth is a common side effect. - Monitor for signs of constipation or difficulty urinating, and contact your veterinarian if these occur.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- As an adjunct to anesthesia
- For bradyarrhythmias
- Associated with anesthesia
- As a premed
- As a premed
- For treatment of bradyarrhythmias
- As a bronchodilator
- To control muscarinic adverse effects associated with imidocarb therapy
- For prevention of bradycardia and to decrease airway and salivary secretions (Rabbits)
- As adjunct to anesthesia (Rabbits)
- As a preanesthetic (Rodents)
- As a preanesthetic (Rabbits)
- As part of an injectable anesthesia protocol in rabbits
給藥方式
可能的副作用
- Dry secretions (xerostomia)
- Initial bradycardia followed by tachycardia
- Decreased gastrointestinal motility (risk of ileus)
- Decreased urinary tract motility
- Mydriasis and cycloplegia
注意事項與禁忌
- Narrow angle glaucoma
- Tachycardias
- Gastrointestinal ileus
- Urinary obstruction
- Hypersensitivity to the drug
- Pregnancy (per some manufacturer labels)
- Use with **extreme caution** in patients with known or suspected GI infections, as decreased GI motility can prolong retention of toxins or causative agents. Use with extreme caution in patients with autonomic neuropathy. Use cautiously in patients with hepatic or renal disease, geriatric or pediatric patients, hyperthyroidism, hypertension, congestive heart failure (CHF), tachyarrhythmias, prostatic hypertrophy, or esophageal reflux. Can produce sinus tachycardia and predispose hypotensive patients to cardiac arrhythmias (including ventricular fibrillation).
藥物相互作用
- Amantadine: May enhance the activity or toxicity of glycopyrrolate.
- Antihistamines (e.g., diphenhydramine): May enhance anticholinergic activity or toxicity.
- Meperidine: May enhance anticholinergic activity or toxicity.
- Phenothiazines: May enhance anticholinergic activity or toxicity.
- Tricyclic Antidepressants (e.g., amitriptyline, clomipramine): May enhance anticholinergic activity or toxicity.
- Amitraz: May aggravate signs seen with amitraz toxicity, leading to hypertension and further inhibition of peristalsis.
- Antacids: May decrease PO absorption; give oral glycopyrrolate at least 1 hour prior to oral antacids.
- Corticosteroids (long-term use): May increase intraocular pressure when used concurrently.
- Digoxin (slow-dissolving): May increase serum digoxin levels; use regular digoxin tablets or oral liquid.
- Ketoconazole: Increased gastric pH may decrease GI absorption; administer 2 hours after ketoconazole.
常見問題
Glycopyrrolate用於寵物有甚麼用途？
- **Parenteral administration** is best performed by professional staff in a clinical setting where adequate cardiac monitoring is available. - If your pet is receiving **glycopyrrolate tablets** at home, allow free access to water and encourage drinking, as dry mouth is a common side effect. - Monitor for signs of constipation or difficulty urinating, and contact your veterinarian if these occur.
Glycopyrrolate對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。