Cefuroxime
別名: Ceftin, Zinacef, Aprokam, Zinnat
* **Give with Food**: Administer the oral tablets with a meal to enhance drug absorption and reduce the chance of stomach upset. * **Do Not Crush**: Avoid crushing the tablets. They have a very strong, bitter taste that pets will reject. If you absolutely must crush them, mix the powder with a strong-tasting dairy product (like milk or pet-safe cheese) to mask the taste and improve absorption. * **Finish the Prescription**: Give the medication exactly as directed by your veterinarian. Continue treating for the full prescribed duration, even if your pet seems completely better, to prevent the infection from returning or becoming resistant. * **Watch for Side Effects**: Contact your veterinarian if your pet develops severe vomiting, persistent diarrhea, rash, itching, or facial swelling.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Soft tissue infections
- Systemic infections
- Meningitis
- Surgery prophylaxis
- Surgical prophylaxis
- Susceptible infections
- Surgical prophylaxis
- Susceptible infections
給藥方式
可能的副作用
- Inappetence
- Vomiting
- Diarrhea
- Injection site inflammation (IV use)
- Eosinophilia
- Hypersensitivity reactions (including anaphylaxis)
- Neurologic effects (hearing loss, seizures - rare)
- Pseudomembranous colitis (rare)
- Serious dermatologic reactions (TEN, Stevens-Johnson syndrome - rare)
- Hematologic effects (pancytopenia, thrombocytopenia - rare)
- Interstitial nephritis (rare)
注意事項與禁忌
- Known hypersensitivity to cefuroxime or other cephalosporins
- > **Renal Impairment**: Dosage adjustment is recommended in patients with severe renal impairment, as the drug is primarily excreted unchanged in the urine. * **Laboratory Interference**: May cause false-positive urine glucose determinations when using the copper reduction method (Benedict's, Fehling's, Clinitest). Tests utilizing glucose oxidase are unaffected. * **Coombs' Test**: Cephalosporins have caused false-positive direct Coombs' tests in humans, particularly those with azotemia. * **Nursing Mothers**: Enters maternal milk in low concentrations; potential for altering gut flora of nursing offspring.
藥物相互作用
- Aminoglycosides: Potential for increased risk of nephrotoxicity; monitor renal function. However, may have synergistic or additive actions against some gram-negative bacteria (Enterobacteriaceae).
- Furosemide: Possible increased risk of nephrotoxicity.
- Torsemide: Possible increased risk of nephrotoxicity.
- Probenecid: Reduced renal excretion of cephalosporins, potentially increasing serum levels.
- Oxytetracycline: Bacteriostatic agents may antagonize the bactericidal activity of cefuroxime.
- Erythromycin: Bacteriostatic agents may antagonize the bactericidal activity of cefuroxime.
- Amphotericin B: Increased risk of nephrotoxicity; monitor renal function.
常見問題
Cefuroxime用於寵物有甚麼用途？
* **Give with Food**: Administer the oral tablets with a meal to enhance drug absorption and reduce the chance of stomach upset. * **Do Not Crush**: Avoid crushing the tablets. They have a very strong, bitter taste that pets will reject. If you absolutely must crush them, mix the powder with a strong-tasting dairy product (like milk or pet-safe cheese) to mask the taste and improve absorption. * **Finish the Prescription**: Give the medication exactly as directed by your veterinarian. Continue treating for the full prescribed duration, even if your pet seems completely better, to prevent the infection from returning or becoming resistant. * **Watch for Side Effects**: Contact your veterinarian if your pet develops severe vomiting, persistent diarrhea, rash, itching, or facial swelling.
Cefuroxime對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。