니아신아마이드

용도

• Discoid lupus erythematosus
• Discoid lupus erythematosus or pemphigus
• Various immune-mediated diseases (DLE, pemphigus, vasculitis, dermatomyositis, etc.)
• Pemphigus foliaceous
• Adjunctive therapy for pemphigus or discoid lupus erythematosus
• Immunomodulation (e.g., lupoid onychodystrophy, discoid lupus erythematosus, pemphigus foliaceus)

투여 방법

가능한 부작용

• Anorexia
• Vomiting
• Lethargy
• Elevated liver enzymes (occasional)
• Increased seizure frequency (anecdotal)
• Mild gastrointestinal irritation (anorexia, vomiting, diarrhea)

주의사항 및 금기

• Liver disease
• Active peptic ulcers
• Hypersensitivity to niacinamide
• Do not use nicotinic acid (niacin) as a substitute due to severe vasodilation (flushing) effects.
• Use with caution in dogs with a history of seizures. While niacinamide alone is generally considered safe in pregnant and lactating animals, its common concurrent use with tetracycline may not be safe during pregnancy/nursing.

약물 상호작용

• Insulin: May require dosage adjustments after initiating niacinamide therapy due to potential alterations in glycemic control.
• Oral Antidiabetic Agents: May require dosage adjustments after initiating niacinamide therapy.

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