저분자량 헤파린 (달테파린, 에녹사파린)

용도

• Thromboembolic complications and hypercoagulable syndromes
• Thromboembolic complications and hypercoagulable syndromes

투여 방법

가능한 부작용

• Haematoma formation (if administered IM)
• Haemorrhage (especially in thrombocytopenic patients or those with DIC)

주의사항 및 금기

• Bleeding disorders
• Severe renal dysfunction
• > **Do not administer intramuscularly (IM)** as it may result in haematoma formation. > Use with extreme caution in patients with DIC, as it may worsen haemorrhage, especially if the patient is thrombocytopenic. > Do not mix other drugs in the same syringe as heparin.

약물 상호작용

• Aspirin: Can cause changes in coagulation status, increasing bleeding risk
• NSAIDs: Can cause changes in coagulation status, increasing bleeding risk
• ACTH: Heparin may antagonize ACTH
• Corticosteroids: Heparin may antagonize corticosteroids
• Insulin: Heparin may antagonize insulin
• Diazepam: Heparin may increase plasma levels of diazepam
• Antihistamines: May partially counteract the actions of heparin
• Digoxin: May partially counteract the actions of heparin
• Tetracyclines: May partially counteract the actions of heparin

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