Tacrolimus
También conocido como: Protopic, Prograf, Advagraf
Wear gloves when applying the ointment to your pet's skin or eyes. Wash hands thoroughly after use. Do not allow other pets to lick the treated area. > **Warning:** If using oral medication, do not switch brands without consulting your veterinarian, as different brands are absorbed differently. Pregnant women should avoid handling this medication if possible.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
Veterinary professional? See the full dosing-by-species reference on VetSheet →
What it is used for
How it is given
Possible side effects
- Topical: local irritation, erythema, pruritus
- Ophthalmic: mild ocular irritation
- Systemic: GI upset (vomiting, diarrhea), nephrotoxicity, neurotoxicity, secondary infections
Cautions & contraindications
- Hypersensitivity to macrolides
- Active systemic infections
- Malignancy (for systemic use)
- > **Warning:** Avoid switching between oral brands due to narrow therapeutic index and variable bioavailability. Wear gloves when applying topical formulations to avoid inadvertent human exposure. Monitor blood levels if used systemically.
Drug interactions
- Ketoconazole: Inhibits CYP3A metabolism, significantly increasing systemic tacrolimus levels
- Erythromycin: Inhibits metabolism, increasing tacrolimus levels
- Grapefruit juice: Increases systemic absorption and blood levels of tacrolimus
Preguntas frecuentes
What is Tacrolimus used for in pets?
Wear gloves when applying the ointment to your pet's skin or eyes. Wash hands thoroughly after use. Do not allow other pets to lick the treated area. > Warning: If using oral medication, do not switch brands without consulting your veterinarian, as different brands are absorbed differently. Pregnant women should avoid handling this medication if possible.
Is Tacrolimus safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
Este artículo es educación general y no sustituye el consejo veterinario profesional. Si tu mascota está mal, consulta a un veterinario.
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