Tripelennamine
Also known as: Re-Covr, Azaron, Etono, Fenistil, PBZ, Pelamine, Pyribenzamine, Vaginex
* **Purpose**: This medication is an antihistamine used to treat allergic reactions, hives, and sometimes utilized as a stimulant in specific cattle conditions (like "Downer cow"). * **Administration**: It is usually given by injection by your veterinarian. If oral forms are prescribed, give exactly as directed. * **Side Effects**: Watch for drowsiness, lack of coordination, or conversely, extreme nervousness and muscle tremors. * **Important Warning**: Do not use in horses intravenously. * **Allergy Testing**: If your pet is scheduled for allergy skin testing, let your veterinarian know they are on this medication, as it needs to be stopped at least 4 days beforehand to ensure accurate test results.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
What it is used for
- General antihistamine
- General antihistamine
- General antihistamine
- Downer Cow Syndrome (Adjunctive treatment)
- General antihistamine
- General antihistamine
- General antihistamine
- General antihistamine
- General antihistamine
- General antihistamine
How it is given
Possible side effects
- CNS stimulation (hyperexcitability, nervousness, muscle tremors) - especially in horses given IV
- CNS depression / Sedation
- Ataxia / Incoordination
- Gastrointestinal disturbances
Cautions & contraindications
- Intravenous (IV) administration in horses is strictly contraindicated due to severe CNS stimulation
- > **WARNING**: Do NOT administer intravenously (IV) to horses due to the risk of severe CNS stimulation, hyperexcitability, and muscle tremors. * **Administration**: It is recommended to warm the injectable solution to near body temperature before injecting. Give IM injections deep into large muscle areas. * **Allergy Testing**: Antihistamines can decrease the wheal and flare response to antigen skin testing. Discontinue at least 4 days prior to intradermal testing to avoid false-negative results. * **Food Animal Residues**: In cattle, meat withdrawal is 4 days following the last treatment. Milk must not be used for food for 24 hours (2 milkings) after treatment.
Drug interactions
- CNS Depressants (e.g., barbiturates, opioids): Increased sedation and CNS depression
- Heparin: May partially counteract the anticoagulation effects
- Warfarin: May partially counteract the anticoagulation effects
Frequently asked questions
What is Tripelennamine used for in pets?
* **Purpose**: This medication is an antihistamine used to treat allergic reactions, hives, and sometimes utilized as a stimulant in specific cattle conditions (like "Downer cow"). * **Administration**: It is usually given by injection by your veterinarian. If oral forms are prescribed, give exactly as directed. * **Side Effects**: Watch for drowsiness, lack of coordination, or conversely, extreme nervousness and muscle tremors. * **Important Warning**: Do not use in horses intravenously. * **Allergy Testing**: If your pet is scheduled for allergy skin testing, let your veterinarian know they are on this medication, as it needs to be stopped at least 4 days beforehand to ensure accurate test results.
Is Tripelennamine safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
This article is for general education and is not a substitute for professional veterinary advice. If your pet is unwell, please consult a veterinarian.
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