Octreotide Acetate
Also known as: Sandostatin, Sandostatin LAR Depot, Longastatina, Samilstin, Sandostatina, Sandostatine
- **Experimental Therapy**: There is very limited experience with this medication in dogs and ferrets and therapy must be considered experimental. - **Administration**: Injections must be given 2-3 times a day per veterinarian instructions. - **Cost**: The expense associated with this medication can be considerable. - **Monitoring**: If treating an insulinoma, monitor your pet closely for signs of low blood sugar (weakness, lethargy, stumbling, or seizures) and contact your veterinarian immediately if these occur.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
What it is used for
- Adjunctive treatment of chylothorax
- Medical treatment of insulinoma (particularly in patients refractory to or unable to tolerate other medical or surgical therapy)
- Medical treatment of insulinoma (beta cell tumor) particularly in patients refractory to or unable to tolerate other medical or surgical therapy
- Medical treatment of insulinoma
- Adjunctive treatment of gastrinoma
- Adjunctive treatment of chylothorax
How it is given
Possible side effects
- Gastrointestinal upset
- Decreased dietary fat absorption
- Biliary sludging or gallstones (with prolonged use)
- Injection site pain
Cautions & contraindications
- Known hypersensitivity to octreotide
- > **Caution**: Use with care in patients with biliary tract disorders or severe renal dysfunction (dosage adjustment may be necessary). Prolonged use (>4 weeks) may increase the risk of gallstone formation. Safety in pregnant or nursing animals is not fully established (FDA Category B in humans).
Drug interactions
- Beta-blockers: May cause additive bradycardic effects
- Bromocriptine: May increase oral bioavailability
- Calcium-channel blockers: May cause additive bradycardic effects
- Cyclosporine: May reduce cyclosporine levels
- Diuretics: May enhance fluid/electrolyte imbalances
- Food: May reduce fat absorption
- Insulin, oral hypoglycemics: Octreotide can inhibit insulin
- Quinidine: May reduce the quinidine clearance
Frequently asked questions
What is Octreotide Acetate used for in pets?
- **Experimental Therapy**: There is very limited experience with this medication in dogs and ferrets and therapy must be considered experimental. - **Administration**: Injections must be given 2-3 times a day per veterinarian instructions. - **Cost**: The expense associated with this medication can be considerable. - **Monitoring**: If treating an insulinoma, monitor your pet closely for signs of low blood sugar (weakness, lethargy, stumbling, or seizures) and contact your veterinarian immediately if these occur.
Is Octreotide Acetate safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
This article is for general education and is not a substitute for professional veterinary advice. If your pet is unwell, please consult a veterinarian.
Worried about your pet?
Peqaboo’s AI helps you track symptoms, understand lab reports, and know when to see a vet.
Get the Peqaboo app