Enoxaparin Sodium
Also known as: Lovenox, Clexane, Decipar, Klexane, Plaucina, Trombenox
Enoxaparin is a blood thinner used to prevent or treat dangerous blood clots. * **Administration:** This medication must be given by subcutaneous (under the skin) injection. Your veterinarian will teach you the proper injection technique. If not using prefilled syringes, use a very small gauge insulin or tuberculin syringe (e.g., 27 gauge). * **Strict Schedule:** It is critical to give this medication exactly as prescribed. If doses are missed or delayed, life-threatening blood clots may form. * **Watch for Bleeding:** Because this drug prevents clotting, there is a risk of bleeding. Immediately report any signs of bleeding (e.g., pale gums, bruising, nosebleeds, dark/tarry stools, or blood in the urine) to your veterinarian. * **Watch for Clots:** Report any sudden weakness, paralysis (especially in the hind legs of cats), pain, or difficulty breathing, as these may be signs of a new blood clot.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
What it is used for
- Anticoagulant therapy
- Anticoagulant therapy
- Anticoagulant therapy
- Anticoagulant therapy
- Anticoagulant therapy
- Anticoagulant therapy
How it is given
Possible side effects
- Hemorrhage (unlikely but possible)
- Injection site hematoma
- Anemia
- Thrombocytopenia
- Nausea
- Fever
- Asymptomatic, reversible increases in AST or ALT
Cautions & contraindications
- Hypersensitivity to enoxaparin, other LMWHs, heparin, or porcine products
- Intramuscular (IM) or Intravenous (IV) administration (must be given SC only)
- Use cautiously in patients with significant **renal dysfunction**, as drug accumulation could result. > **Important:** Do NOT administer via IM or IV routes; enoxaparin must be given via deep subcutaneous injection only. Enoxaparin cannot be used interchangeably with other LMWHs (e.g., dalteparin) or unfractionated heparin sodium because the dosages and anti-Xa activities differ for each product.
Drug interactions
- Warfarin (Oral Anticoagulants): Increased risk for hemorrhage
- Aspirin: Increased risk for hemorrhage
- Clopidogrel: Increased risk for hemorrhage
- Thrombolytic Agents: Increased risk for hemorrhage
Frequently asked questions
What is Enoxaparin Sodium used for in pets?
Enoxaparin is a blood thinner used to prevent or treat dangerous blood clots. * **Administration:** This medication must be given by subcutaneous (under the skin) injection. Your veterinarian will teach you the proper injection technique. If not using prefilled syringes, use a very small gauge insulin or tuberculin syringe (e.g., 27 gauge). * **Strict Schedule:** It is critical to give this medication exactly as prescribed. If doses are missed or delayed, life-threatening blood clots may form. * **Watch for Bleeding:** Because this drug prevents clotting, there is a risk of bleeding. Immediately report any signs of bleeding (e.g., pale gums, bruising, nosebleeds, dark/tarry stools, or blood in the urine) to your veterinarian. * **Watch for Clots:** Report any sudden weakness, paralysis (especially in the hind legs of cats), pain, or difficulty breathing, as these may be signs of a new blood clot.
Is Enoxaparin Sodium safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
This article is for general education and is not a substitute for professional veterinary advice. If your pet is unwell, please consult a veterinarian.
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