Altrenogest
Also known as: Regu-Mate, Matrix
### ⚠️ CRITICAL HANDLING WARNINGS This medication can be easily absorbed through intact human skin and poses severe health risks to certain individuals. **DO NOT HANDLE THIS MEDICATION IF YOU ARE:** - Pregnant or suspect you might be pregnant - A person with a history of blood clots, stroke, or heart disease - A person with a history of breast cancer or estrogen-dependent tumors - Experiencing undiagnosed vaginal bleeding **Handling Instructions:** - Always wear protective, non-porous gloves when handling the medication or equipment used to administer it. - If the medication accidentally contacts your skin, **wash it off immediately** with soap and water. - If it gets in your eyes, flush with water for 15 minutes and seek medical attention. - If accidentally swallowed, do not induce vomiting; contact a physician or poison control center immediately. **Pet Care Instructions:** - Administer exactly as prescribed by your veterinarian. - Store the medication away from direct light.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
What it is used for
- To suppress estrus for synchronization
- For prevention of abortion/pregnancy loss
- To maintain pregnancy in mares with deficient progesterone levels
- To maintain pregnancy in mares with placentitis
- To suppress estrus (long-term)
- For synchronization of estrous in sexually mature gilts that have had at least one estrous cycle
- Luteal insufficiency
- Luteal insufficiency, pre-term labor
- To maintain pregnancy if tocolytics (e.g., terbutaline) do not control myometrial contractility
How it is given
Possible side effects
- Minimal at labeled dosages
- Slight, sporadic elevations in Ca++, K+, alkaline phosphatase, and AST
- May exacerbate chronic uterine infections
- Risk of pyometra in dogs (due to exogenous progesterone effects)
Cautions & contraindications
- Horses intended for food purposes
- Mares with chronic uterine infections
- Manufacturer lists pregnancy as a contraindication (though clinically used extensively to maintain pregnancy)
- ### Human Handling Warnings Altrenogest can be absorbed through intact skin, and absorption is enhanced under occlusive materials (e.g., latex gloves). The following individuals **MUST NOT** handle this product: - Women who are or suspect they are pregnant - Anyone with a history of thrombophlebitis or thromboembolic disorders - Anyone with cerebrovascular or coronary artery disease - Women with known or suspected breast carcinoma - People with known or suspected estrogen-dependent neoplasias - Women with undiagnosed vaginal bleeding - People with tumors that developed during the use of oral contraceptives If skin exposure occurs, wash immediately with soap and water. If eye exposure occurs, flush with water for 15 minutes and seek medical attention.
Drug interactions
- Rifampin: May decrease progestin activity if administered concomitantly due to microsomal enzyme induction and increased progestin metabolism.
Frequently asked questions
What is Altrenogest used for in pets?
### ⚠️ CRITICAL HANDLING WARNINGS This medication can be easily absorbed through intact human skin and poses severe health risks to certain individuals. **DO NOT HANDLE THIS MEDICATION IF YOU ARE:** - Pregnant or suspect you might be pregnant - A person with a history of blood clots, stroke, or heart disease - A person with a history of breast cancer or estrogen-dependent tumors - Experiencing undiagnosed vaginal bleeding **Handling Instructions:** - Always wear protective, non-porous gloves when handling the medication or equipment used to administer it. - If the medication accidentally contacts your skin, **wash it off immediately** with soap and water. - If it gets in your eyes, flush with water for 15 minutes and seek medical attention. - If accidentally swallowed, do not induce vomiting; contact a physician or poison control center immediately. **Pet Care Instructions:** - Administer exactly as prescribed by your veterinarian. - Store the medication away from direct light.
Is Altrenogest safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
This article is for general education and is not a substitute for professional veterinary advice. If your pet is unwell, please consult a veterinarian.
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