알트레노게스트

용도

• To suppress estrus for synchronization
• For prevention of abortion/pregnancy loss
• To maintain pregnancy in mares with deficient progesterone levels
• To maintain pregnancy in mares with placentitis
• To suppress estrus (long-term)
• For synchronization of estrous in sexually mature gilts that have had at least one estrous cycle
• Luteal insufficiency
• Luteal insufficiency, pre-term labor
• To maintain pregnancy if tocolytics (e.g., terbutaline) do not control myometrial contractility

투여 방법

가능한 부작용

• Minimal at labeled dosages
• Slight, sporadic elevations in Ca++, K+, alkaline phosphatase, and AST
• May exacerbate chronic uterine infections
• Risk of pyometra in dogs (due to exogenous progesterone effects)

주의사항 및 금기

• Horses intended for food purposes
• Mares with chronic uterine infections
• Manufacturer lists pregnancy as a contraindication (though clinically used extensively to maintain pregnancy)
• ### Human Handling Warnings Altrenogest can be absorbed through intact skin, and absorption is enhanced under occlusive materials (e.g., latex gloves). The following individuals **MUST NOT** handle this product: - Women who are or suspect they are pregnant - Anyone with a history of thrombophlebitis or thromboembolic disorders - Anyone with cerebrovascular or coronary artery disease - Women with known or suspected breast carcinoma - People with known or suspected estrogen-dependent neoplasias - Women with undiagnosed vaginal bleeding - People with tumors that developed during the use of oral contraceptives If skin exposure occurs, wash immediately with soap and water. If eye exposure occurs, flush with water for 15 minutes and seek medical attention.

약물 상호작용

• Rifampin: May decrease progestin activity if administered concomitantly due to microsomal enzyme induction and increased progestin metabolism.

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