司維拉姆
別名: Renagel, Renvela
藥物類別: Phosphorus Binding Agent
> **關鍵用藥時間**：此藥物**必須隨餐服用**才能發揮作用。它就像海綿一樣，會在食物中的磷進入寵物體內之前將其吸收。 * **與其他藥物分開**：司維拉姆會阻礙其他藥物的吸收。請在給予司維拉姆前至少 **1 小時**或後 **3 小時**再給予其他藥物。 * **維生素補充**：您的獸醫可能會建議補充維生素，因為此藥物會減少食物中維生素的吸收。 * **副作用**：請留意腸胃不適的跡象，如嘔吐、腹瀉或便秘。如果出現這些情況，請聯繫您的獸醫。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- Hyperphosphatemia
- Chronic kidney disease (hyperphosphataemia)
- Hyperphosphatemia
- Chronic kidney disease (hyperphosphataemia)
給藥方式
PO
可能的副作用
- Gastrointestinal upset (nausea, vomiting, diarrhea, or constipation)
- Decreased absorption of fat-soluble vitamins (A, D, E, K) and folic acid
- Constipation
- Pills are hygroscopic and will expand (potential risk of esophageal obstruction if not swallowed quickly)
注意事項與禁忌
- Hypophosphatemia
- Bowel obstruction
- Known hypersensitivity to sevelamer
- Gastrointestinal obstruction
- > **Pregnancy & Nursing**: Safety during pregnancy is not established (FDA Category C). Because of the potential for binding vitamins, additional vitamins (both fat and water-soluble) may be necessary for pregnant or nursing animals. * **Vitamin K Deficiency**: Because sevelamer can bind fat-soluble vitamins, it may impact Vitamin K absorption, potentially affecting coagulation. * **Administration Timing**: Must be given with meals to be effective at binding dietary phosphorus.
藥物相互作用
- Anticonvulsants (oral): Sevelamer may reduce oral absorption; give at least 1 hour before or 3 hours after sevelamer.
- Antiarrhythmics (oral): Sevelamer may reduce oral absorption; give at least 1 hour before or 3 hours after sevelamer.
- Ciprofloxacin (and other oral fluoroquinolones): Concurrent administration may decrease absorption by 50%; administer at least 1 hour before or 3 hours after sevelamer.
- Oral Medications (Narrow Therapeutic Index): May reduce absorption; consider dosing other oral drugs separately.
- Vitamins: Sevelamer may reduce vitamin absorption from food; consider administering vitamin supplements separately.
- Other oral medications: May bind to and decrease the absorption of concurrently administered oral drugs. Should be given at least 1 hour before or 3 hours after other medications.
- Fat-soluble vitamins (e.g., Vitamin K): May inhibit vitamin absorption; consider monitoring prothrombin time.
常見問題
司維拉姆用於寵物有什麼用途？
> 關鍵用藥時間：此藥物必須隨餐服用才能發揮作用。它就像海綿一樣，會在食物中的磷進入寵物體內之前將其吸收。 • 與其他藥物分開：司維拉姆會阻礙其他藥物的吸收。請在給予司維拉姆前至少 1 小時或後 3 小時再給予其他藥物。 • 維生素補充：您的獸醫可能會建議補充維生素，因為此藥物會減少食物中維生素的吸收。 • 副作用：請留意腸胃不適的跡象，如嘔吐、腹瀉或便秘。如果出現這些情況，請聯繫您的獸醫。
司維拉姆對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。