Sevelamer
別名: Renagel, Renvela
> **Crucial Timing**: This medication **must be given with meals** to work properly. It acts like a sponge to soak up the phosphorus in your pet's food before it can enter their body. * **Separate from other medications**: Sevelamer can prevent other drugs from being absorbed. Give other medications at least **1 hour before** or **3 hours after** giving sevelamer. * **Vitamins**: Your veterinarian may recommend a vitamin supplement, as this drug can reduce the absorption of vitamins from food. * **Side Effects**: Watch for signs of stomach upset, such as vomiting, diarrhea, or constipation. Contact your veterinarian if these occur.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Hyperphosphatemia
- Chronic kidney disease (hyperphosphataemia)
- Hyperphosphatemia
- Chronic kidney disease (hyperphosphataemia)
給藥方式
可能的副作用
- Gastrointestinal upset (nausea, vomiting, diarrhea, or constipation)
- Decreased absorption of fat-soluble vitamins (A, D, E, K) and folic acid
- Constipation
- Pills are hygroscopic and will expand (potential risk of esophageal obstruction if not swallowed quickly)
注意事項與禁忌
- Hypophosphatemia
- Bowel obstruction
- Known hypersensitivity to sevelamer
- Gastrointestinal obstruction
- > **Pregnancy & Nursing**: Safety during pregnancy is not established (FDA Category C). Because of the potential for binding vitamins, additional vitamins (both fat and water-soluble) may be necessary for pregnant or nursing animals. * **Vitamin K Deficiency**: Because sevelamer can bind fat-soluble vitamins, it may impact Vitamin K absorption, potentially affecting coagulation. * **Administration Timing**: Must be given with meals to be effective at binding dietary phosphorus.
藥物相互作用
- Anticonvulsants (oral): Sevelamer may reduce oral absorption; give at least 1 hour before or 3 hours after sevelamer.
- Antiarrhythmics (oral): Sevelamer may reduce oral absorption; give at least 1 hour before or 3 hours after sevelamer.
- Ciprofloxacin (and other oral fluoroquinolones): Concurrent administration may decrease absorption by 50%; administer at least 1 hour before or 3 hours after sevelamer.
- Oral Medications (Narrow Therapeutic Index): May reduce absorption; consider dosing other oral drugs separately.
- Vitamins: Sevelamer may reduce vitamin absorption from food; consider administering vitamin supplements separately.
- Other oral medications: May bind to and decrease the absorption of concurrently administered oral drugs. Should be given at least 1 hour before or 3 hours after other medications.
- Fat-soluble vitamins (e.g., Vitamin K): May inhibit vitamin absorption; consider monitoring prothrombin time.
常見問題
Sevelamer用於寵物有甚麼用途？
> **Crucial Timing**: This medication **must be given with meals** to work properly. It acts like a sponge to soak up the phosphorus in your pet's food before it can enter their body. * **Separate from other medications**: Sevelamer can prevent other drugs from being absorbed. Give other medications at least **1 hour before** or **3 hours after** giving sevelamer. * **Vitamins**: Your veterinarian may recommend a vitamin supplement, as this drug can reduce the absorption of vitamins from food. * **Side Effects**: Watch for signs of stomach upset, such as vomiting, diarrhea, or constipation. Contact your veterinarian if these occur.
Sevelamer對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。