艾司洛爾
別名: Brevibloc, Miniblock
藥物類別: Beta-1 Adrenergic Blocker (Ultra-short acting)
艾司洛爾是一種急救用的超短效藥物，僅在獸醫院環境中施打。 * **持續監測：** 您的寵物在接受此藥物時，將會接受心電圖 (ECG) 和血壓設備的密切監測。 * **用途：** 它通常用於迅速穩定危險的心律，或作為「測試」，以觀察您的寵物心臟狀況是否對長效口服 Beta 阻斷劑有良好反應。 * **安全性：** 因為它在幾分鐘內就會從血液中清除，任何副作用（如低血壓或心跳過慢）通常在停止輸注後會非常迅速地消退。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- HCM (to determine if beta-blockers will reduce dynamic left-ventricular outflow tract obstruction)
- Critical Arrhythmias
- Ultra-short acting beta blockade (ventricular arrhythmias) - Normal cardiac function
- Ultra-short acting beta blockade - Severe dilated cardiomyopathy or severe mitral regurgitation
- SVTs
- Arrhythmia conversion
給藥方式
IV
可能的副作用
- Hypotension
- Bradycardia
- Heart block
- Exacerbation of congestive heart failure
- Bronchospasm (at high doses where beta-1 selectivity is lost)
注意事項與禁忌
- Overt cardiac failure
- 2nd or 3rd degree AV block
- Sinus bradycardia
- Cardiogenic shock
- Second or third-degree AV block
- Uncompensated congestive heart failure
- Hypotension
- Use with caution (weigh benefit vs. risk) in patients with congestive heart failure (CHF), bronchoconstrictive lung disease, or diabetes mellitus. Esmolol may mask certain clinical signs of developing hypoglycemia (such as increased heart rate or blood pressure).
藥物相互作用
- Digoxin: Esmolol may increase serum digoxin levels up to 20%, but these drugs have been used together safely and effectively.
- Monoamine Oxidase Inhibitors (MAOIs): Concurrent use is not recommended due to potential risk of hypertension.
- Morphine: May increase steady-state esmolol serum concentrations up to 50%; titrate esmolol dosage carefully.
- Reserpine: May see additive effects (hypotension, bradycardia) if used with esmolol.
- Vasoconstrictors/Inotropes (e.g., dopamine, epinephrine, norepinephrine): If systemic vascular resistance is high, there is an increased risk for blocked cardiac contractility; esmolol is not recommended to control SVTs in patients receiving these drugs.
- Verapamil: In humans, particularly with severe cardiomyopathy, cardiac arrest has occurred (rarely).
- Calcium channel blockers (e.g., Diltiazem, Verapamil): Additive negative inotropic and chronotropic effects; risk of severe bradycardia and hypotension
- Alpha-2 agonists (e.g., Dexmedetomidine): Increased risk of severe bradycardia
- Sympathomimetics (e.g., Epinephrine): Mutual antagonism
常見問題
艾司洛爾用於寵物有什麼用途？
艾司洛爾是一種急救用的超短效藥物，僅在獸醫院環境中施打。 * **持續監測：** 您的寵物在接受此藥物時，將會接受心電圖 (ECG) 和血壓設備的密切監測。 * **用途：** 它通常用於迅速穩定危險的心律，或作為「測試」，以觀察您的寵物心臟狀況是否對長效口服 Beta 阻斷劑有良好反應。 * **安全性：** 因為它在幾分鐘內就會從血液中清除，任何副作用（如低血壓或心跳過慢）通常在停止輸注後會非常迅速地消退。
艾司洛爾對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。