頭孢他啶
別名: Fortaz, Ceptaz, Tazicef, Tazidime, Fortum
藥物類別: 3rd Generation Cephalosporin Antibiotic
- **給藥方式**：您的獸醫可能會指示您在家中為寵物進行皮下注射 (SC)。請確保您了解正確的注射技巧。 - **儲存方式**：請嚴格遵守獸醫的儲存指示。如果提供的是冷凍針筒，請保存在冷凍庫中，僅在需要時於室溫下解凍單劑量。**解凍後的藥劑請勿再次冷凍**。 - **副作用**：如果您的寵物出現嚴重的腸胃不適（腹瀉、嘔吐）或過敏反應（如面部腫脹、呼吸困難），請立即聯繫獸醫。 - **注射部位**：觀察注射部位是否有紅腫或疼痛的跡象。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Initial antibiotic therapy of gram-negative infections
- Initial treatment of orthopedic infections
- Initial treatment of soft tissue infections
- Initial treatment of sepsis, bacteremia
- Susceptible infections
- Pseudomonas aeruginosa infections
- Pseudomonas aeruginosa infections (CRI)
- Initial treatment of systemic infections
- Susceptible infections
- Pseudomonas infections
- Susceptible infections
- Bacterial infections in snakes (particularly Enterobacteriaceae or Pseudomonas aeruginosa)
- Chelonians
給藥方式
IMIVSCIntraosseous
可能的副作用
- Pain at IM injection site (SC may be less painful)
- Gastrointestinal effects (diarrhea, vomiting)
- Hypersensitivity reactions (allergic reactions)
- Granulocytopenia
- Thrombocytopenia
- Mild azotemia
- Pseudomembranous colitis (C. difficile)
- Increased serum liver enzymes (reported in humans)
注意事項與禁忌
- Known hypersensitivity or prior allergic reaction to cephalosporins
- > **Renal Impairment:** Because the drug is primarily excreted via the kidneys, accumulation may result in patients with significantly impaired renal function. Use with caution and adjust the dose as required. - **Cross-Reactivity:** Up to 16% of humans allergic to penicillins may also be allergic to cephalosporins; the veterinary significance is unclear but warrants caution. - **Laboratory Interference:** May cause a false-positive urine glucose determination when using cupric sulfate solution tests (e.g., Clinitest). May rarely cause positive direct Coombs' tests.
藥物相互作用
- Aminoglycosides / Nephrotoxic drugs (e.g., amphotericin B): Potential additive nephrotoxicity. In vitro synergy exists against certain bacteria, but they must NOT be mixed in the same syringe or fluid bag (administer separately).
- Chloramphenicol: May be antagonistic to ceftazidime's bactericidal effects on gram-negative bacilli; concurrent use is not recommended.
- Oxytetracycline: Bacteriostatic agents may antagonize the bactericidal activity of ceftazidime.
- Erythromycin: Bacteriostatic agents may antagonize the bactericidal activity of ceftazidime.
- Amphotericin B: Increased risk of nephrotoxicity when used concurrently.
- Furosemide: Loop diuretics may increase the risk of nephrotoxicity.
- Aminoglycosides: Synergistic in vivo against Pseudomonas; however, chemically incompatible in vitro (do not mix in the same syringe).
常見問題
頭孢他啶用於寵物有什麼用途？
- **給藥方式**：您的獸醫可能會指示您在家中為寵物進行皮下注射 (SC)。請確保您了解正確的注射技巧。 - **儲存方式**：請嚴格遵守獸醫的儲存指示。如果提供的是冷凍針筒，請保存在冷凍庫中，僅在需要時於室溫下解凍單劑量。**解凍後的藥劑請勿再次冷凍**。 - **副作用**：如果您的寵物出現嚴重的腸胃不適（腹瀉、嘔吐）或過敏反應（如面部腫脹、呼吸困難），請立即聯繫獸醫。 - **注射部位**：觀察注射部位是否有紅腫或疼痛的跡象。
頭孢他啶對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。