Tolazoline
別名: Tolazine, Priscol, Priscoline, Vaso-Dilatan
Tolazoline is a medication administered exclusively by veterinary professionals to "wake up" (reverse the sedation of) your animal after a procedure or examination. * **What to Expect**: As your animal wakes up, you may notice temporary side effects such as sweating, lip smacking or licking, anxiety, or muscle twitching. * **Duration**: These effects are generally mild and should diminish and disappear within 2 hours of dosing. * **Safety**: Because of the rapid changes in heart rate and blood pressure that can occur, your animal will be closely monitored by the veterinary team during the recovery period.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- For reversal of xylazine effects
- For reversal of xylazine effects
- For reversal of xylazine effects
- For reversal of xylazine effects
- For reversal of xylazine effects
- For reversal of xylazine effects
- For reversal of xylazine effects (Emergency)
- For reversal of xylazine effects
- As a reversal agent for alpha2-adrenergic agonists (e.g., xylazine, detomidine, etc.)
- For reversal of xylazine effects
給藥方式
可能的副作用
- Transient tachycardia
- Peripheral vasodilation (sweating, injected mucous membranes of gingiva and conjunctiva)
- Hyperalgesia of the lips (licking, flipping of lips)
- Piloerection
- Clear lacrimal and nasal discharge
- Muscle fasciculations
- Apprehensiveness and anxiety
- Gastrointestinal hypermotility (flatulence, diarrhea, mild colic)
注意事項與禁忌
- Horses exhibiting signs of stress, debilitation, or shock
- Cardiac disease or coronary artery disease
- Sympathetic blockage
- Hypovolemia
- Cerebrovascular disease
- Known hypersensitivity to the drug
- Foals (relative contraindication; adverse reactions and fatalities reported)
- > **WARNING: Rapid IV Administration** > Acute death and cardiac asystole have been reported after rapid IV administration of tolazoline at high dosages, particularly in camelids and cattle. Always administer IV slowly (e.g., 1 mL/second) or consider the IM route. * **High Concentration Risk**: The veterinary formulation is highly concentrated (100 mg/mL), making accurate dosing difficult in small animals (dogs/cats). Yohimbine or atipamezole are generally safer alternatives for small animals. * **Human Safety**: Humans with coronary artery or cerebrovascular disease should use extra caution when handling this agent.
藥物相互作用
- Alcohol: Accumulation of acetaldehyde can occur if tolazoline and alcohol are given simultaneously.
- Epinephrine: If large doses of tolazoline are given with epinephrine, a paradoxical drop in blood pressure can occur followed by a precipitous increase in blood pressure.
- Norepinephrine: If large doses of tolazoline are given with norepinephrine, a paradoxical drop in blood pressure can occur followed by a precipitous increase in blood pressure.
常見問題
Tolazoline用於寵物有甚麼用途？
Tolazoline is a medication administered exclusively by veterinary professionals to "wake up" (reverse the sedation of) your animal after a procedure or examination. * **What to Expect**: As your animal wakes up, you may notice temporary side effects such as sweating, lip smacking or licking, anxiety, or muscle twitching. * **Duration**: These effects are generally mild and should diminish and disappear within 2 hours of dosing. * **Safety**: Because of the rapid changes in heart rate and blood pressure that can occur, your animal will be closely monitored by the veterinary team during the recovery period.
Tolazoline對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。