Sodium Bicarbonate
別名: Baking soda, Neut, Zegerid
**Sodium Bicarbonate** (commonly known as baking soda) is used medically to make your pet's blood or urine less acidic. - **Administration**: If giving oral tablets or powder, follow your veterinarian's exact dosing. **Do not substitute household baking soda** unless specifically instructed by your vet, as dosing can be imprecise and potentially dangerous. - **Timing with Other Meds**: Give this medication at least **12 hours apart** from other oral medications if possible, as it changes stomach acid levels and can severely affect how other drugs are absorbed. - **Monitoring**: Your vet will likely need to check your pet's blood work or urine pH regularly to ensure the dose is correct and safe. - **Side Effects to Watch For**: Watch for signs of fluid retention (like rapid breathing, coughing, or swelling), muscle twitching, or weakness. Contact your vet immediately if you notice any unusual behavior or symptoms.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Acidosis (Ruminants)
- Acidosis (Ruminants)
- Severe metabolic acidosis
- Metabolic acidosis secondary to uremia
- Adjunctive therapy of diabetic ketoacidosis
- Adjunctive treatment of hypercalcemic crisis
- Adjunctive therapy for hyperkalemic crises
- To alkalinize the urine
- Acidosis
- Severely dehydrated acidotic calves
- Metabolic acidosis (associated with colic)
- Metabolic acidosis
- Severe metabolic acidosis
給藥方式
可能的副作用
- Metabolic alkalosis
- Hypokalemia
- Hypocalcemia
- 'Overshoot' alkalosis
- Hypernatremia
- Volume overload
- Congestive heart failure
- Shifts in the oxygen dissociation curve (decreased tissue oxygenation)
- Paradoxical CNS acidosis leading to respiratory arrest
- Hypercapnia (if not well ventilated during CPR)
- Predisposition to ventricular fibrillation
- Hypernatraemia
- Congestive heart failure (due to sodium load)
- Decreased tissue oxygenation (shift in oxygen dissociation curve)
注意事項與禁忌
- Metabolic or respiratory alkalosis
- Excessive chloride loss secondary to vomiting or GI suction
- Patients at risk for development of diuretic-induced hypochloremic alkalosis
- Hypocalcemia (alkalosis may induce tetany)
- Hypoventilating patients
- Hypercapnoeic patients
- Animals unable to effectively expel carbon dioxide
- **Extreme Caution**: Use with extreme caution and give very slowly in patients with hypocalcemia to avoid inducing tetany. **Caution**: Because of the potential sodium load, use with caution in patients with congestive heart failure (CHF), nephrotic syndrome, hypertension, oliguria, acute renal failure, or volume overload. **Ventilation**: When used during CPR, ensure the patient is well ventilated to prevent hypercapnia and paradoxical CNS acidosis.
藥物相互作用
- Anticholinergic agents: Concomitant oral sodium bicarbonate may reduce absorption; administer separately
- Azole antifungals (ketoconazole, itraconazole): Concomitant oral sodium bicarbonate may reduce absorption; administer separately
- Ciprofloxacin, Enrofloxacin: Solubility is decreased in an alkaline environment; monitor for signs of crystalluria
- Corticosteroids: Patients receiving high dosages of sodium bicarbonate and ACTH or glucocorticoids may develop hypernatremia
- Diuretics (e.g., thiazides, furosemide): Concurrent use in patients receiving potassium-wasting diuretics may cause hypochloremic alkalosis
- Ephedrine: When urine is alkalinized, excretion may be decreased
- Histamine2 blocking agents (e.g., cimetidine, ranitidine): Concomitant oral sodium bicarbonate may reduce absorption; administer separately
- Iron products: Concomitant oral sodium bicarbonate may reduce absorption; administer separately
- Oral medications (general): Can increase or reduce absorption rate/extent; avoid giving other drugs within 12 hours of oral sodium bicarbonate
- Quinidine: When urine is alkalinized, excretion may be decreased
常見問題
Sodium Bicarbonate用於寵物有甚麼用途?
**Sodium Bicarbonate** (commonly known as baking soda) is used medically to make your pet's blood or urine less acidic. - **Administration**: If giving oral tablets or powder, follow your veterinarian's exact dosing. **Do not substitute household baking soda** unless specifically instructed by your vet, as dosing can be imprecise and potentially dangerous. - **Timing with Other Meds**: Give this medication at least **12 hours apart** from other oral medications if possible, as it changes stomach acid levels and can severely affect how other drugs are absorbed. - **Monitoring**: Your vet will likely need to check your pet's blood work or urine pH regularly to ensure the dose is correct and safe. - **Side Effects to Watch For**: Watch for signs of fluid retention (like rapid breathing, coughing, or swelling), muscle twitching, or weakness. Contact your vet immediately if you notice any unusual behavior or symptoms.
Sodium Bicarbonate對我的寵物安全嗎?
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育,不能取代專業獸醫意見。如寵物身體不適,請諮詢獸醫。