Potassium bromide
別名: Bromilep, Epilease, Libromide
**Important Information for Pet Owners:** * **Dietary Consistency is Crucial:** The amount of salt in your dog's diet directly affects how this medication works. Do not change your dog's food, and be very careful with treats or table scraps. A sudden increase in salt will cause the drug to be flushed out of the body, potentially leading to seizures. * **Patience is Needed:** This drug takes a very long time (up to 3-4 months) to reach its full, stable effect in the body unless your vet uses a high "loading dose" initially. * **Side Effects:** Increased thirst, increased appetite, and increased urination are common. During the first few weeks, or if a loading dose is used, your dog may appear very sleepy, wobbly, or uncoordinated. Contact your vet if this is severe. * **NEVER GIVE TO CATS:** This medication is highly toxic to cats and can cause a fatal lung condition.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Control of seizures (Maintenance)
- Control of seizures (5-day Loading Dose)
- Control of seizures (Single Loading Dose)
- Control of seizures (Intrarectal Loading)
- Contraindicated
給藥方式
可能的副作用
- Ataxia
- Sedation
- Somnolence
- Vomiting (especially with high concentration solutions >250 mg/ml)
- Polyphagia
- Polydipsia
- Pancreatitis
- Skin reactions (in animals with pre-existing skin diseases)
- Behavioural changes (irritability, restlessness)
- Transient diarrhoea (with intrarectal loading)
注意事項與禁忌
- Cats (causes severe, potentially fatal eosinophilic bronchitis)
- Dogs with a history of, or predisposition to, pancreatitis
- > **Dietary Consistency:** High levels of dietary salt increase renal elimination of bromide. It is critical that the patient's diet (including treats) be kept strictly constant once bromide therapy has started. > **Laboratory Artifact:** Bromide is measured in assays for chloride and will produce falsely high 'chloride' results. > **Renal Impairment:** Use with caution in dogs with renal disease, as bromide is eliminated by the kidneys. > **Loading Dose Risks:** Loading doses are associated with an increased incidence of adverse effects (sedation, ataxia) and should only be used in dogs with poorly controlled severe seizures.
藥物相互作用
- Dietary salt (Sodium chloride): Increased dietary salt increases renal elimination of bromide, decreasing serum bromide concentrations.
- Chloride-containing IV fluids: Increases bromide excretion and lowers serum bromide levels.
- Loop diuretics (e.g., furosemide): Increases bromide excretion and decreases serum bromide concentrations.
- Phenobarbital: Synergistic GABA-ergic anticonvulsant effects.
常見問題
Potassium bromide用於寵物有甚麼用途？
**Important Information for Pet Owners:** * **Dietary Consistency is Crucial:** The amount of salt in your dog's diet directly affects how this medication works. Do not change your dog's food, and be very careful with treats or table scraps. A sudden increase in salt will cause the drug to be flushed out of the body, potentially leading to seizures. * **Patience is Needed:** This drug takes a very long time (up to 3-4 months) to reach its full, stable effect in the body unless your vet uses a high "loading dose" initially. * **Side Effects:** Increased thirst, increased appetite, and increased urination are common. During the first few weeks, or if a loading dose is used, your dog may appear very sleepy, wobbly, or uncoordinated. Contact your vet if this is severe. * **NEVER GIVE TO CATS:** This medication is highly toxic to cats and can cause a fatal lung condition.
Potassium bromide對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。