米索前列醇
別名: Cytotec, Arthotec, Arthrotec, Artotec, Artrenac Pro, Condrotec, Corrigast, Cyprostol, Cytolog, Diclotec, Glefos, Menpros, Misodex, Misofenac, Napratec, Normulen, Oxaprost, Symbol
> **孕婦的重大警告**：此藥物可能引起子宮收縮和流產。孕婦或準備懷孕的女性**絕對不應**接觸此藥物。如果必須處理，必須採取嚴格的預防措施（例如戴上拋棄式手套）。 * **胃腸道不適**：最常見的副作用是腹瀉、腹部絞痛和嘔吐。這些症狀通常是暫時的，會隨著寵物身體適應藥物而在幾天內緩解。 * **給藥方式**：將此藥物與食物一起餵食有助於減少胃部不適和腹瀉。 * **何時聯繫獸醫師**：如果腹瀉變得嚴重、持續超過幾天，或者您的寵物變得昏昏欲睡，請聯繫您的獸醫師。他們可能需要調整劑量或建議使用特定的制酸劑（請避免使用含鎂的制酸劑，因為它們會加重腹瀉）。 * **雌性寵物**：如果給予未結紮的雌性犬隻，由於藥物對子宮的作用，您可能會注意到陰道出血或分泌物。
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- Induction of abortion
- Adjunctive treatment of acute colitis
- Equine gastric ulcer syndrome
- Induce cervical relaxation (post-breeding endometritis)
- Prevention of aspirin-induced gastric injury
- Prevention or treatment of gastric ulceration from NSAIDs
- Prevention or treatment of gastric ulceration from NSAIDs
- Preventing GI mucosal injury in dogs with arthritis requiring long-term NSAID therapy; treating gastro-duodenal ulcer disease caused by NSAIDS
- Adjunctive therapy for the termination of mid-term pregnancy
- Treating pyometra/metritis
- Abortifacient protocol after mismating
- Adjunctive therapy for atopic dermatitis
- Adjunctive therapy for atopic dermatitis
- Management of pre-existing NSAID-induced gastric ulceration (extrapolated from human dosing)
- Prophylaxis to prevent NSAID-induced ulceration
- Induction of abortion
給藥方式
可能的副作用
- Diarrhea
- Abdominal pain
- Vomiting
- Flatulence
- Uterine contractions (in females)
- Vaginal bleeding (in females)
- Diarrhoea
- Nausea
- Abortion
注意事項與禁忌
- Pregnancy (unless being used specifically as an abortifacient)
- Nursing mothers (can cause severe diarrhea in nursing offspring)
- Known sensitivity to prostaglandins or prostaglandin analogs
- Pregnant animals (unless being used specifically to induce abortion)
- > **WARNING FOR PREGNANT WOMEN**: Misoprostol is a potent abortifacient. Pregnant women or women who may become pregnant should handle this drug with extreme caution (e.g., wearing gloves or avoiding handling altogether). * Use with caution in patients with **cerebral or coronary vascular disease**. While not explicitly reported with misoprostol, other prostaglandins have precipitated seizures in epileptic patients and caused hypotension. * Adverse GI effects are common but often transient; they can be minimized by adjusting the dose or administering the drug with food.
藥物相互作用
- Magnesium-containing antacids: May aggravate misoprostol-induced diarrhea. If an antacid is required, an aluminum-only antacid is preferred.
- Gentamicin: May exacerbate renal dysfunction
- Diclofenac: Human combination products (misoprostol + diclofenac) are highly toxic to small animals due to different NSAID pharmacokinetics
常見問題
米索前列醇用於寵物有甚麼用途？
> 孕婦的重大警告：此藥物可能引起子宮收縮和流產。孕婦或準備懷孕的女性絕對不應接觸此藥物。如果必須處理，必須採取嚴格的預防措施（例如戴上拋棄式手套）。 • 胃腸道不適：最常見的副作用是腹瀉、腹部絞痛和嘔吐。這些症狀通常是暫時的，會隨著寵物身體適應藥物而在幾天內緩解。 • 給藥方式：將此藥物與食物一起餵食有助於減少胃部不適和腹瀉。 • 何時聯繫獸醫師：如果腹瀉變得嚴重、持續超過幾天，或者您的寵物變得昏昏欲睡，請聯繫您的獸醫師。他們可能需要調整劑量或建議使用特定的制酸劑（請避免使用含鎂的制酸劑，因為它們會加重腹瀉）。 • 雌性寵物：如果給予未結紮的雌性犬隻，由於藥物對子宮的作用，您可能會注意到陰道出血或分泌物。
米索前列醇對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。