Milbemycin Oxime
別名: Interceptor, Sentinel, Milbemite
- **Compliance is key**: Give this medication exactly as prescribed, usually once a month on the same day. - **Watch them eat it**: Ensure your pet completely consumes the tablet. If they spit it out, they will not be protected. - **Testing required**: Your pet must have a negative heartworm test before starting this medication. - **Side effects**: Very rare at standard monthly doses. If your pet is being treated for mange at higher daily doses, watch for and immediately report any stumbling, tremors, excessive drooling, or extreme lethargy.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Prevention of heartworm; treat adult hookworm and adult roundworms
- Heartworm prophylaxis, control of adult hookworms, roundworms, and whipworms
- Microfilaricide chemotherapy (in adulticide-pretreated dogs)
- Treatment of generalized demodicosis
- Treatment of cheyletiellosis
- Treatment of scabies
- Chronic rhinitis caused by Pneumonyssus caninum
- Nematodes
給藥方式
可能的副作用
- Transient shock-like syndrome (in microfilaremic animals)
- Ataxia
- Trembling
- Mydriasis
- Hypersalivation
- Lethargy
- Pyrexia
- Seizures
- Coma
注意事項與禁忌
- Puppies less than 4 weeks of age or less than 2 lbs
- Kittens less than 6 weeks of age or less than 1.5 lbs
- Because some dogs with a high number of circulating microfilaria will develop a transient, shock-like syndrome after receiving milbemycin, testing for preexisting heartworm infections is recommended before use. If using at doses greater than labeled in breeds susceptible to the ABCB1 genetic mutation, genetic testing is recommended before initiating therapy. Safety in breeding, pregnant, and lactating queens and breeding toms has not been established.
藥物相互作用
- Benzodiazepines: Effects may be potentiated by milbemycin; concurrent use is not advised in humans and warrants caution in animals.
- P-glycoprotein inhibitors (Amiodarone, Ketoconazole, Cyclosporine, Diltiazem, Erythromycin, Clarithromycin, Quinidine, Spironolactone, Tamoxifen, Verapamil): May inhibit the efflux pump at the blood-brain barrier, increasing the risk of milbemycin neurotoxicity, particularly in dogs at risk for the ABCB1-1 (MDR1) mutation.
常見問題
Milbemycin Oxime用於寵物有甚麼用途？
- **Compliance is key**: Give this medication exactly as prescribed, usually once a month on the same day. - **Watch them eat it**: Ensure your pet completely consumes the tablet. If they spit it out, they will not be protected. - **Testing required**: Your pet must have a negative heartworm test before starting this medication. - **Side effects**: Very rare at standard monthly doses. If your pet is being treated for mange at higher daily doses, watch for and immediately report any stumbling, tremors, excessive drooling, or extreme lethargy.
Milbemycin Oxime對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。