Melarsomine
別名: Immiticide, Diroban
> **CRITICAL WARNING: STRICT CAGE REST IS MANDATORY.** * **Exercise Restriction**: As the adult heartworms die, they break apart and are carried into the lungs. Any increase in heart rate (from walking, playing, or excitement) forces these worm fragments deeper into the small blood vessels of the lungs, causing a potentially fatal blockage (pulmonary thromboembolism). Your dog must be kept strictly confined to a cage or small room for several weeks after treatment. * **Injection Site Pain**: The medication is given via a deep injection into the back muscles. It is normal for your dog to be sore, reluctant to move, or have a small lump at the injection site. * **What to Watch For**: Monitor your dog closely for coughing, gagging, fever, lethargy, or loss of appetite. * **Emergency Signs**: If your dog experiences severe difficulty breathing, pale or blue gums, or collapses, seek emergency veterinary care immediately.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Heartworm disease (Class I & II)
- Heartworm disease (Class III)
- Heartworm disease (Alternative Protocol / AHS Treatment of Choice)
給藥方式
可能的副作用
- Injection site reactions (pain, swelling, tenderness, firm nodules)
- Coughing/gagging
- Depression/lethargy
- Anorexia/inappetence
- Excessive salivation
- Fever
- Lung congestion
- Vomiting
- Pulmonary thromboembolism (can be fatal)
- Paresis and paralysis (rare)
注意事項與禁忌
- Class IV (very severe) heartworm disease / Caval syndrome
- Cats (reportedly very toxic)
- Intravenous (IV) administration
- Subcutaneous (SC) administration
- Low margin of safety; calculate dosages very carefully (do not confuse mg/lb with mg/kg). Administer ONLY via deep IM injection in the lumbar epaxial muscles (L3-L5). Do NOT give IV or SC, as significant toxicity or tissue necrosis may occur. Strict cage rest (2-4 weeks) is mandatory to prevent fatal pulmonary thromboembolism. Older dogs (>8 years) and those with severe pulmonary artery disease are at higher risk for adverse effects. Avoid human exposure; wash hands after use or wear gloves. If human exposure occurs, contact a physician.
藥物相互作用
- Aspirin: Has been shown not to reduce adverse effects and may complicate therapy; use is not recommended.
- CNS Depressant Drugs: Drugs that have similar adverse effects (e.g., depression) may cause additive adverse effects or increase their incidence when used with melarsomine.
常見問題
Melarsomine用於寵物有甚麼用途？
> **CRITICAL WARNING: STRICT CAGE REST IS MANDATORY.** * **Exercise Restriction**: As the adult heartworms die, they break apart and are carried into the lungs. Any increase in heart rate (from walking, playing, or excitement) forces these worm fragments deeper into the small blood vessels of the lungs, causing a potentially fatal blockage (pulmonary thromboembolism). Your dog must be kept strictly confined to a cage or small room for several weeks after treatment. * **Injection Site Pain**: The medication is given via a deep injection into the back muscles. It is normal for your dog to be sore, reluctant to move, or have a small lump at the injection site. * **What to Watch For**: Monitor your dog closely for coughing, gagging, fever, lethargy, or loss of appetite. * **Emergency Signs**: If your dog experiences severe difficulty breathing, pale or blue gums, or collapses, seek emergency veterinary care immediately.
Melarsomine對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。