Griseofulvin
別名: Fulvicin, AmTech Griseofulvin, Grifulvin V, Gris-PEG
> **Important:** Griseofulvin can cause birth defects. Pregnant women should avoid handling this medication, or wear gloves if administration is necessary. * **Administration:** Always give this medication with a **fatty meal** (e.g., a small amount of canned food, butter, or corn oil) to help the body absorb it properly. * **Compliance:** Ringworm treatment takes time. Continue giving the medication exactly as prescribed, even if the pet looks better. Stopping too early can cause the infection to return. * **Environmental Control:** Ringworm is highly contagious to other pets and humans. Follow your veterinarian's instructions for disinfecting the home, destroying old bedding, and isolating the pet if necessary. * **Side Effects:** Watch for loss of appetite, vomiting, or diarrhea. If your pet seems lethargic, uncoordinated, or develops any unusual symptoms, contact your veterinarian immediately.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Susceptible dermatophytic infections
- Susceptible dermatophytic infections
- Susceptible dermatophytic infections
- Feline eosinophilic granuloma complex
- Susceptible dermatophytic infections
- Susceptible dermatophytic infections
- Susceptible dermatophytic infections
- Susceptible dermatophytic infections (Ratites)
- Susceptible dermatophytic infections
- Advanced dermatophytosis (Rabbits)
- Susceptible dermatophytic infections (Chinchillas)
- Susceptible dermatophytic infections (Gerbils, Guinea pigs, Hamsters, Rats)
- Susceptible dermatophytic infections (Mice)
給藥方式
可能的副作用
- Anorexia
- Vomiting
- Diarrhea
- Anemia
- Neutropenia
- Leukopenia
- Thrombocytopenia
- Depression
- Ataxia
- Hepatotoxicity
- Dermatitis/photosensitivity
- Toxic epidermal necrolysis
- Teratogenesis
注意事項與禁忌
- Pregnancy (known teratogen)
- Known hypersensitivity to griseofulvin
- Hepatocellular failure
- Horses intended for food
- **Important Warnings:** * **Feline Sensitivity:** Cats, particularly kittens, are highly susceptible to adverse effects (e.g., bone marrow depression), likely due to slower glucuronide conjugation. Monitor carefully. * **FIV Testing:** Cats should be tested for FIV before initiating therapy due to the drug's potential neutropenic or panleukopenic effects. * **Teratogenicity:** Griseofulvin is a known teratogen (causes cleft palate, skeletal/brain malformations). It is strictly contraindicated in pregnant animals. It may also inhibit spermatogenesis. * **Absorption:** Must be given with a fatty meal to ensure adequate GI absorption.
藥物相互作用
- Alcohol: Griseofulvin may potentiate the effects of alcohol.
- Aspirin: Griseofulvin may decrease salicylate levels.
- Cyclosporine: Griseofulvin may decrease cyclosporine levels.
- Phenobarbital: May decrease griseofulvin blood concentrations by inducing hepatic microsomal enzymes and/or reducing absorption. Dosage adjustment may be necessary.
- Theophylline: May decrease theophylline half-life and levels in some patients.
- Warfarin: May reduce the anticoagulant activity of coumarin anticoagulants; adjustment may be required.
常見問題
Griseofulvin用於寵物有甚麼用途？
> **Important:** Griseofulvin can cause birth defects. Pregnant women should avoid handling this medication, or wear gloves if administration is necessary. * **Administration:** Always give this medication with a **fatty meal** (e.g., a small amount of canned food, butter, or corn oil) to help the body absorb it properly. * **Compliance:** Ringworm treatment takes time. Continue giving the medication exactly as prescribed, even if the pet looks better. Stopping too early can cause the infection to return. * **Environmental Control:** Ringworm is highly contagious to other pets and humans. Follow your veterinarian's instructions for disinfecting the home, destroying old bedding, and isolating the pet if necessary. * **Side Effects:** Watch for loss of appetite, vomiting, or diarrhea. If your pet seems lethargic, uncoordinated, or develops any unusual symptoms, contact your veterinarian immediately.
Griseofulvin對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。