Fludrocortisone
別名: Florinef
* **Do not stop abruptly:** This medication is life-saving and must be given exactly as prescribed. Missing doses can lead to a life-threatening Addisonian crisis. * **Stressful events:** Your pet may need extra medication (like prednisolone) during stressful times (boarding, surgery, illness, travel). Consult your vet beforehand. * **Monitoring:** Regular blood tests are essential to ensure the dose is correct, especially in the first year of treatment. * **Side effects:** Watch for excessive thirst, increased urination, weight gain, or swelling, and report these to your veterinarian.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Hypoadrenocorticism (Addison's disease)
- Hypoadrenocorticism (Addison's disease)
給藥方式
可能的副作用
- Hypertension
- Oedema (including cerebral oedema)
- Hypokalaemia
- Hypercortisolism / Iatrogenic Cushing's syndrome (with long-term overdose)
- Polyuria/polydipsia (PU/PD)
- Clinical signs of hypercortisolism (with long-term overdose)
注意事項與禁忌
- No specific contraindications listed in the monograph, but use with caution in patients with congestive heart failure, severe hypertension, or renal disease.
- No specific contraindications available in the monograph, but generally contraindicated in patients with systemic fungal infections or known hypersensitivity.
- * Monitor **absolute sodium and potassium concentrations** (not just the Na:K ratio) 4-6 hours post-pill. * If dosing q24h, check Na/K concentrations pre-pill. * Supplemental doses of prednisolone may be required at times of metabolic or physical stress. * Some formulations require refrigeration. * **Clinical Pearl:** Dose requirements often increase over the first 6-18 months of therapy as residual adrenal function ceases.
藥物相互作用
- Amphotericin B: Increased risk of severe hypokalaemia
- Furosemide: Increased risk of hypokalaemia due to additive potassium-depleting effects
- Thiazide diuretics: Increased risk of hypokalaemia due to additive potassium-depleting effects
常見問題
Fludrocortisone用於寵物有甚麼用途？
* **Do not stop abruptly:** This medication is life-saving and must be given exactly as prescribed. Missing doses can lead to a life-threatening Addisonian crisis. * **Stressful events:** Your pet may need extra medication (like prednisolone) during stressful times (boarding, surgery, illness, travel). Consult your vet beforehand. * **Monitoring:** Regular blood tests are essential to ensure the dose is correct, especially in the first year of treatment. * **Side effects:** Watch for excessive thirst, increased urination, weight gain, or swelling, and report these to your veterinarian.
Fludrocortisone對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。