Felbamate
別名: Felbatol, Taloxa, Felbamyl
* **Strict Schedule**: It is critical to give this medication exactly as prescribed, usually **every 8 hours (three times a day)**. Because it leaves the body quickly, missing doses can lead to breakthrough seizures. * **Side Effects**: Watch for signs of dry eye (squinting, thick eye discharge), tremors, restlessness, or vomiting. Contact your veterinarian if you notice these signs. * **Blood Tests**: Your veterinarian may recommend periodic blood tests to monitor liver function and blood cell counts, especially if your dog is taking other seizure medications. * **Do Not Stop Abruptly**: Never stop seizure medications suddenly without consulting your veterinarian, as this can trigger severe, life-threatening seizures.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Seizures (As either add-on therapy or monotherapy)
- Seizures (As a third choice antiepileptic agent)
- Seizures (For patients on phenobarb and bromides and seizure activity unchanged or having intolerable side effects)
給藥方式
可能的副作用
- Keratoconjunctivitis sicca (KCS)
- Liver enzyme induction
- Tremor
- Limb rigidity
- Salivation
- Restlessness and agitation (at high doses)
- Blood dyscrasias (thrombocytopenia, lymphopenia, leukopenia)
- Sedation (usually when combined with other anticonvulsants)
- Vomiting/nausea (usually when combined with other anticonvulsants)
注意事項與禁忌
- Hypersensitivity to felbamate or other carbamates (e.g., meprobamate)
- > **Warning**: May cause liver enzyme induction. Half-life may decrease over time, requiring dose adjustments. * Use with caution in patients with pre-existing **hepatic dysfunction** or a history of **blood dyscrasias**. * **Pregnancy Category C**: Use only if potential benefits outweigh risks. Excreted in maternal milk, but adverse consequences to nursing puppies appear remote.
藥物相互作用
- Phenobarbital: Felbamate may increase phenobarbital levels. Phenobarbital may decrease felbamate levels.
- Phenytoin: Felbamate may increase phenytoin levels. Phenytoin may decrease felbamate levels.
- Valproate: Felbamate can cause increases in valproic acid levels.
常見問題
Felbamate用於寵物有甚麼用途？
* **Strict Schedule**: It is critical to give this medication exactly as prescribed, usually **every 8 hours (three times a day)**. Because it leaves the body quickly, missing doses can lead to breakthrough seizures. * **Side Effects**: Watch for signs of dry eye (squinting, thick eye discharge), tremors, restlessness, or vomiting. Contact your veterinarian if you notice these signs. * **Blood Tests**: Your veterinarian may recommend periodic blood tests to monitor liver function and blood cell counts, especially if your dog is taking other seizure medications. * **Do Not Stop Abruptly**: Never stop seizure medications suddenly without consulting your veterinarian, as this can trigger severe, life-threatening seizures.
Felbamate對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。