Edetate Calcium Disodium
別名: Calcium Disodium Versenate, Calcium Vitis, Calciumedetat-Heyl, Chelante, Chelintox, Ledclair, CaEDTA
Heavy metal poisoning (such as from eating pennies, lead paint, or metallic hardware) is a serious, potentially life-threatening emergency. * **Hospitalization Required:** Because of the potential toxicity of this antidote and the severity of heavy metal intoxication, your pet will likely need to stay in the hospital for close professional supervision, injections, and IV fluids. * **Kidney Protection:** The drug works by binding the metal and forcing it out through the urine. IV fluids are critical to help flush the kidneys and protect them from damage. * **Multiple Treatments:** Treatment often requires several days of injections, followed by a rest period, and potentially another round of injections depending on follow-up blood tests.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Lead poisoning (Psittacines)
- Lead poisoning (Raptors/Falcons)
- Lead or zinc poisoning
- Lead poisoning
- Lead poisoning
- Lead poisoning
- Zinc toxicity
- Lead or zinc toxicity
- Heavy metal toxicity (Chinchillas)
- Lead poisoning
- Lead or zinc toxicity
- Lead poisoning
- Lead poisoning
- Lead poisoning
給藥方式
可能的副作用
- Renal toxicity (renal tubular necrosis)
- Depression (dogs)
- Vomiting
- Diarrhea
- Zinc deficiency (with chronic therapy)
- Pain at IM injection site
注意事項與禁忌
- Patients with anuria
- Oral (PO) administration in the presence of lead in the GI tract (enhances absorption)
- Use with **extreme caution** in patients with diminished renal function; dosage adjustments are required. In small animals, the **SC route is strongly preferred**. IV administration has been associated with abrupt increases in CSF pressure and death in human pediatric patients with lead-induced cerebral edema. **Do not administer orally** if lead is still present in the GI tract, as it will facilitate systemic absorption of the lead. Remove lead from the GI tract (via emesis, endoscopy, or surgery) prior to starting chelation. Ensure adequate hydration to protect the kidneys, but avoid overhydration in animals showing clinical signs of cerebral edema.
藥物相互作用
- Glucocorticoids: May enhance the renal toxicity of CaEDTA
- Insulin (NPH, PZI): Concurrent administration will decrease the sustained action of the insulin preparation due to zinc chelation
- Nephrotoxic drugs (e.g., aminoglycosides, amphotericin B): Increased risk of nephrotoxicity; use with extreme caution
常見問題
Edetate Calcium Disodium用於寵物有甚麼用途？
Heavy metal poisoning (such as from eating pennies, lead paint, or metallic hardware) is a serious, potentially life-threatening emergency. * **Hospitalization Required:** Because of the potential toxicity of this antidote and the severity of heavy metal intoxication, your pet will likely need to stay in the hospital for close professional supervision, injections, and IV fluids. * **Kidney Protection:** The drug works by binding the metal and forcing it out through the urine. IV fluids are critical to help flush the kidneys and protect them from damage. * **Multiple Treatments:** Treatment often requires several days of injections, followed by a rest period, and potentially another round of injections depending on follow-up blood tests.
Edetate Calcium Disodium對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。