Diphenoxylate and Atropine
別名: Lomotil, Logen, Lonox, Lomanate, co-phenotrope
### Important Information for Pet Owners * **Purpose**: This medication is used to treat diarrhea or to suppress a chronic, hacking cough in dogs. * **When to Call the Vet**: Contact your veterinarian immediately if the diarrhea persists for more than 48 hours, if your pet becomes extremely lethargic/listless, develops a high fever, or shows signs of abdominal pain. * **Watch for Constipation**: Because this drug slows down the gut, it can cause constipation, especially when used long-term for coughing. Let your vet know if your pet is straining to defecate; a stool softener may be needed. * **Dosing Accuracy**: If you have a small dog and are using the liquid form, measure the dose *very carefully*. Overdosing can cause serious side effects, including severe drowsiness and breathing problems. * **Storage**: Keep this medication strictly out of reach of children and other pets. It is a controlled substance.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- As an antidiarrheal
- As an antidiarrheal
- As an antidiarrheal
- As an antidiarrheal
- As an antidiarrheal
- As an antitussive
- As an antitussive
給藥方式
可能的副作用
- Constipation
- Bloat
- Sedation
- Paralytic ileus (potential)
- Toxic megacolon (potential)
- Pancreatitis (potential)
- CNS depression or excitation
- Excitatory behavior (especially in cats)
注意事項與禁忌
- Known hypersensitivity to narcotic analgesics
- Patients receiving monoamine oxidase inhibitors (MAOIs)
- Diarrhea caused by toxic ingestion (until the toxin is eliminated from the GI tract)
- Intestinal obstruction
- Bacterial-induced acute diarrhea (may enhance bacterial proliferation)
- Use with caution in patients with **respiratory disease**, **hepatic encephalopathy** (hepatic coma may result), **hypothyroidism**, **severe renal insufficiency**, **adrenocortical insufficiency (Addison's disease)**, **head injuries or increased intracranial pressure**, **acute abdominal conditions** (may obscure diagnosis), and in **geriatric or severely debilitated patients**. * **Small Dogs**: Extreme care is required when dosing dogs under 10 kg; liquid formulations are recommended for accurate titration. * **Cats**: Use is controversial and generally not recommended due to potential excitatory behavior. * **Horses/Infectious Diarrhea**: Opiates may have a detrimental effect in acute diarrhea by enhancing bacterial proliferation, delaying microbe clearance, and prolonging the febrile state. * **Nursing/Pregnancy**: Category C. Excreted in maternal milk; use caution in nursing patients.
藥物相互作用
- CNS Depressant Drugs (anesthetics, antihistamines, phenothiazines, barbiturates, tranquilizers, alcohol): May cause increased CNS or respiratory depression when used concurrently.
- Monoamine Oxidase Inhibitors (MAOIs) (e.g., amitraz, selegiline): Contraindicated. Do not use opiate antidiarrheals for at least 14 days after receiving MAOIs due to risk of severe adverse reactions.
常見問題
Diphenoxylate and Atropine用於寵物有甚麼用途？
### Important Information for Pet Owners * **Purpose**: This medication is used to treat diarrhea or to suppress a chronic, hacking cough in dogs. * **When to Call the Vet**: Contact your veterinarian immediately if the diarrhea persists for more than 48 hours, if your pet becomes extremely lethargic/listless, develops a high fever, or shows signs of abdominal pain. * **Watch for Constipation**: Because this drug slows down the gut, it can cause constipation, especially when used long-term for coughing. Let your vet know if your pet is straining to defecate; a stool softener may be needed. * **Dosing Accuracy**: If you have a small dog and are using the liquid form, measure the dose *very carefully*. Overdosing can cause serious side effects, including severe drowsiness and breathing problems. * **Storage**: Keep this medication strictly out of reach of children and other pets. It is a controlled substance.
Diphenoxylate and Atropine對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。