Dantrolene Sodium
別名: Dantrium, Danlene, Dantamacrin, Dantralen, Dantrolen
* **Expected Effects:** Dantrolene can cause mild gastrointestinal upset (vomiting, lack of appetite), increased urinary frequency, and sedation (drowsiness or weakness). * **Liver Warning:** Rarely, dantrolene can cause liver toxicity. **Contact your veterinarian immediately** if your pet develops persistent vomiting, loss of appetite, unexplained profound lethargy, or yellowish discoloration of the whites of the eyes or gums (jaundice). * **Administration:** Intravenous use of this drug should only be performed by veterinary professionals familiar with its use and monitoring requirements.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Treatment of functional urethral obstruction due to increased external urethral tone
- Treatment of functional urethral obstruction due to increased external urethral tone
- Treatment of functional urethral obstruction due to increased external urethral tone
- Treatment of functional urethral obstruction due to increased external urethral tone
- Treatment of acute rhabdomyolysis
- Treatment of acute rhabdomyolysis
- Prevention of recurrent exertional rhabdomyolysis in Thoroughbreds
- Prevention of rhabdomyolysis
- Prevention of rhabdomyolysis
- Prevention of rhabdomyolysis
- Prevention of rhabdomyolysis
- Prevention of post-anesthetic myositis (PAM)
給藥方式
可能的副作用
- Weakness
- Sedation
- Dizziness
- Headache
- Nausea
- Vomiting
- Constipation
- Increased urinary frequency
- Hypotension
- Hepatotoxicity (especially with chronic use)
注意事項與禁忌
- Preexisting liver disease (use with extreme caution)
- Severe cardiac dysfunction (use with caution)
- Pulmonary disease (use with caution)
- > **Hepatotoxicity Warning:** Dantrolene can cause hepatotoxicity. It should be used with extreme caution in patients with preexisting liver disease. Monitor liver enzymes closely during chronic therapy. * Use with caution in patients with severe cardiac dysfunction or pulmonary disease. * **Pregnancy:** FDA Category C (human); Papich Class C (veterinary). Use cautiously as a last resort when benefits clearly outweigh risks. * **Nursing:** Distributed into milk; safe use cannot be assured during nursing.
藥物相互作用
- Benzodiazepines & other CNS depressants: Increased sedation may be seen if tranquilizing agents are used concomitantly.
- Calcium-Channel Blockers: Rare reports of cardiovascular collapse in humans; concomitant use during malignant hyperthermia crises is not recommended.
- Estrogens: Increased risks of hepatotoxicity have been seen in women >35 years of age; veterinary significance is unknown.
- Warfarin: Dantrolene may be displaced from plasma proteins by warfarin, resulting in increased effects or adverse reactions.
常見問題
Dantrolene Sodium用於寵物有甚麼用途？
* **Expected Effects:** Dantrolene can cause mild gastrointestinal upset (vomiting, lack of appetite), increased urinary frequency, and sedation (drowsiness or weakness). * **Liver Warning:** Rarely, dantrolene can cause liver toxicity. **Contact your veterinarian immediately** if your pet develops persistent vomiting, loss of appetite, unexplained profound lethargy, or yellowish discoloration of the whites of the eyes or gums (jaundice). * **Administration:** Intravenous use of this drug should only be performed by veterinary professionals familiar with its use and monitoring requirements.
Dantrolene Sodium對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。