Cimetidine
別名: Zitac, Tagamet
**Cimetidine** is used to treat stomach ulcers, acid reflux, and conditions where the stomach produces too much acid. * **Do not stop this medication abruptly**, as it can cause a rebound in stomach acid production. Your vet will likely instruct you to taper the dose gradually when stopping treatment. * If you are also giving sucralfate, antacids, or certain other medications, separate the doses by at least 2 hours to ensure both drugs are absorbed properly. * Side effects are rare, but contact your veterinarian if you notice any unusual signs, such as unexplained bruising (which could indicate low platelets) or swelling of the mammary glands in female dogs.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- All uses (gastritis, ulcers, oesophagitis, hypersecretory conditions)
- All uses (gastritis, ulcers, oesophagitis, hypersecretory conditions)
給藥方式
可能的副作用
- Thrombocytopenia (reported in dogs)
- Transient and self-resolving slight swelling of mammary glands (female dogs)
- Hepatotoxicity (rare, reported in humans)
- Nephrotoxicity (rare, reported in humans)
- Headache (humans)
- Decreased libido (humans)
注意事項與禁忌
- No specific contraindications available, but use with caution in patients with known hypersensitivity.
- > **Warning:** Rebound gastric acid secretion may be seen on cessation of cimetidine, so therapy should be tapered. Concomitant treatment with sucralfate may be helpful. > **Warning:** If used IV, should be administered slowly over 30 minutes to prevent cardiac arrhythmias and hypotension. * Dosage should be reduced for animals with renal impairment.
藥物相互作用
- Propranolol: Increases plasma levels of beta-blockers due to CYP450 inhibition
- Verapamil: Increases plasma levels of calcium-channel blockers
- Diazepam: Increases plasma levels of diazepam
- Lidocaine: Increases plasma levels of lidocaine
- Metronidazole: Increases plasma levels of metronidazole
- Pethidine: Increases plasma levels of pethidine
- Theophylline: Increases plasma levels of theophylline
- Myelosuppressive agents: May exacerbate leucopenia
- Sucralfate: May decrease cimetidine bioavailability; administer sucralfate at least 2 hours before
- Antacids: May decrease absorption; stagger oral doses by 2 hours
- Digoxin: Altered absorption/metabolism; stagger oral doses by 2 hours
- Itraconazole: Decreased absorption of itraconazole due to reduced gastric acidity; stagger oral doses by 2 hours
常見問題
Cimetidine用於寵物有甚麼用途？
**Cimetidine** is used to treat stomach ulcers, acid reflux, and conditions where the stomach produces too much acid. * **Do not stop this medication abruptly**, as it can cause a rebound in stomach acid production. Your vet will likely instruct you to taper the dose gradually when stopping treatment. * If you are also giving sucralfate, antacids, or certain other medications, separate the doses by at least 2 hours to ensure both drugs are absorbed properly. * Side effects are rare, but contact your veterinarian if you notice any unusual signs, such as unexplained bruising (which could indicate low platelets) or swelling of the mammary glands in female dogs.
Cimetidine對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。