Bethanechol
別名: Urecholine, Myotonine
> **Important**: Bethanechol helps your pet's bladder muscle contract so they can urinate properly. It is often used when the bladder has become overstretched or weak. - **Administration**: Give exactly as prescribed. Do not increase the dose without consulting your veterinarian. - **What to Watch For**: Because this drug stimulates the "rest and digest" system, you might notice side effects commonly remembered by the acronym **SLUD** (Salivation, Lacrimation/tearing, Urination, Defecation). Mild vomiting or diarrhea can also occur. - **When to Call the Vet**: Contact your veterinarian immediately if your pet experiences severe vomiting, diarrhea, excessive drooling, difficulty breathing, or seems unusually weak. - **Safety Warning**: Never give this medication if your pet is straining but unable to pass urine (blocked), as forcing the bladder to contract against a blockage could cause severe damage or rupture.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
給藥方式
可能的副作用
- Salivation
- Lacrimation
- Urination
- Defecation
- Vomiting
- Diarrhea
- Anorexia
- Bradycardia (high dose/SC)
- Arrhythmias (high dose/SC)
- Hypotension (high dose/SC)
- Asthma/Dyspnea (high dose/SC)
- Abdominal pain (horses)
注意事項與禁忌
- Bladder neck or urinary outflow obstruction
- Questionable bladder wall integrity (e.g., recent bladder surgery)
- Hyperthyroidism
- Peptic ulcer disease or inflammatory GI lesions
- Recent GI surgery with resections/anastomoses
- GI obstruction or peritonitis
- Hypersensitivity to bethanechol
- Epilepsy
- Asthma
- Coronary artery disease or occlusion
- Hypotension
- Severe bradycardia
- Vagotonia or vasomotor instability
- > **Important Outflow Warning**: If urinary outflow resistance is increased due to enhanced urethral tone (not mechanical obstruction), bethanechol should **only** be used in conjunction with another agent that will sufficiently reduce outflow resistance (e.g., diazepam, dantrolene for striated muscle, or phenoxybenzamine for smooth muscle). - **Route Warnings**: IM or IV use is not recommended except in emergencies when the IV route may be used. Severe cholinergic reactions are likely if given IV. - **Antidote Readiness**: If injecting the drug (SC or IV), it is highly recommended that **atropine** be immediately available to treat potential cholinergic crisis.
藥物相互作用
- Anticholinergic drugs (e.g., atropine, glycopyrrolate, propantheline): Can antagonize bethanechol's effects
- Other cholinergic drugs: Additive toxicity and increased risk of cholinergic crisis
- Atropine: Antagonizes the effects of bethanechol
常見問題
Bethanechol用於寵物有甚麼用途？
> **Important**: Bethanechol helps your pet's bladder muscle contract so they can urinate properly. It is often used when the bladder has become overstretched or weak. - **Administration**: Give exactly as prescribed. Do not increase the dose without consulting your veterinarian. - **What to Watch For**: Because this drug stimulates the "rest and digest" system, you might notice side effects commonly remembered by the acronym **SLUD** (Salivation, Lacrimation/tearing, Urination, Defecation). Mild vomiting or diarrhea can also occur. - **When to Call the Vet**: Contact your veterinarian immediately if your pet experiences severe vomiting, diarrhea, excessive drooling, difficulty breathing, or seems unusually weak. - **Safety Warning**: Never give this medication if your pet is straining but unable to pass urine (blocked), as forcing the bladder to contract against a blockage could cause severe damage or rupture.
Bethanechol對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。