베타네콜

용도

투여 방법

가능한 부작용

• Salivation
• Lacrimation
• Urination
• Defecation
• Vomiting
• Diarrhea
• Anorexia
• Bradycardia (high dose/SC)
• Arrhythmias (high dose/SC)
• Hypotension (high dose/SC)
• Asthma/Dyspnea (high dose/SC)
• Abdominal pain (horses)

주의사항 및 금기

• Bladder neck or urinary outflow obstruction
• Questionable bladder wall integrity (e.g., recent bladder surgery)
• Hyperthyroidism
• Peptic ulcer disease or inflammatory GI lesions
• Recent GI surgery with resections/anastomoses
• GI obstruction or peritonitis
• Hypersensitivity to bethanechol
• Epilepsy
• Asthma
• Coronary artery disease or occlusion
• Hypotension
• Severe bradycardia
• Vagotonia or vasomotor instability
• > **Important Outflow Warning**: If urinary outflow resistance is increased due to enhanced urethral tone (not mechanical obstruction), bethanechol should **only** be used in conjunction with another agent that will sufficiently reduce outflow resistance (e.g., diazepam, dantrolene for striated muscle, or phenoxybenzamine for smooth muscle). - **Route Warnings**: IM or IV use is not recommended except in emergencies when the IV route may be used. Severe cholinergic reactions are likely if given IV. - **Antidote Readiness**: If injecting the drug (SC or IV), it is highly recommended that **atropine** be immediately available to treat potential cholinergic crisis.

약물 상호작용

• Anticholinergic drugs (e.g., atropine, glycopyrrolate, propantheline): Can antagonize bethanechol's effects
• Other cholinergic drugs: Additive toxicity and increased risk of cholinergic crisis
• Atropine: Antagonizes the effects of bethanechol

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