Aglepristone
別名: Alizin, Alizine
- **Veterinary Administration Only**: Only veterinary professionals should handle and administer this product due to severe risks associated with accidental human injection. - **Pregnancy Termination**: When used for pregnancy termination in the bitch, understand that aglepristone might only be 95% effective when used between days 26-45. - **Vaginal Discharge**: A brown mucoid vaginal discharge can be seen approximately 24 hours before fetal expulsion. - **Side Effects**: Your pet may exhibit lack of appetite, excitement, restlessness or depression, vomiting, or diarrhea after treatment. - **When to Call the Vet**: Contact your veterinarian if your pet exhibits a purulent (pus-like) or hemorrhagic (bloody) discharge after treatment, or if vaginal discharge persists 3 weeks after treatment. - **Pyometra Treatment**: When used for pyometra, there is a substantial risk of treatment failure, and surgical removal of the uterus and ovaries (spay) may ultimately be required.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- To terminate pregnancy (up to day 45)
- To induce parturition
- To induce parturition
- As an adjunct to treating pyometra/metritis (preserve fertility)
- For closed cervix pyometra
- For metritis
- For open or closed pyometra
- For pyometra
- Pregnancy termination
- Progesterone-induced acromegaly
- Pyometra
- For treating mammary fibroadenomatous hyperplasia
- For treating mammary fibroadenomatous hyperplasia
給藥方式
可能的副作用
- Injection site reactions (pain, edema, skin thickening, ulceration, localized lymph node enlargement)
- Anorexia (25%)
- Excitation (23%)
- Depression (21%)
- Diarrhea (13%)
- Uterine infections (3.4%)
- Vomiting (2%)
- Brown mucoid vaginal discharge (associated with pregnancy termination)
- Mammary gland congestion
注意事項與禁忌
- Known hypersensitivity to aglepristone
- Pregnancy (unless used specifically for pregnancy termination or inducing parturition)
- Hypoadrenocorticism (Addison's disease) or genetic predisposition to it
- Peritonitis (must be ruled out before using for pyometra)
- Caution in patients with poor health, diabetes, or impaired hepatic/renal function
- > **WARNING**: Accidental injection of this product can induce abortion; it should not be administered or handled by pregnant women. Accidental injection can also cause severe pain, intense swelling, and ischemic necrosis that can lead to serious sequelae, including loss of a digit. Seek prompt medical attention if accidentally injected. * **Injection Site Care**: Light massage of the injection site is recommended after administration. Larger dogs should not receive more than 5 mL at any one SC injection site. Administering into the scruff of the neck may help avoid severe injection reactions. * **Pyometra**: When used for pyometra, there is a substantial risk of treatment failure, and ovariohysterectomy may ultimately be required.
藥物相互作用
- Progestins (natural or synthetic): Could reduce the efficacy of aglepristone
- Glucocorticoids: Aglepristone could reduce the efficacy of glucocorticoid treatment due to receptor antagonism
- Ketoconazole: May interact with aglepristone (manufacturer warning, likely due to CYP450 enzyme inhibition)
- Itraconazole: May interact with aglepristone (manufacturer warning)
- Erythromycin: May interact with aglepristone (manufacturer warning)
常見問題
Aglepristone用於寵物有甚麼用途？
- **Veterinary Administration Only**: Only veterinary professionals should handle and administer this product due to severe risks associated with accidental human injection. - **Pregnancy Termination**: When used for pregnancy termination in the bitch, understand that aglepristone might only be 95% effective when used between days 26-45. - **Vaginal Discharge**: A brown mucoid vaginal discharge can be seen approximately 24 hours before fetal expulsion. - **Side Effects**: Your pet may exhibit lack of appetite, excitement, restlessness or depression, vomiting, or diarrhea after treatment. - **When to Call the Vet**: Contact your veterinarian if your pet exhibits a purulent (pus-like) or hemorrhagic (bloody) discharge after treatment, or if vaginal discharge persists 3 weeks after treatment. - **Pyometra Treatment**: When used for pyometra, there is a substantial risk of treatment failure, and surgical removal of the uterus and ovaries (spay) may ultimately be required.
Aglepristone對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。