Phenylpropanolamine
Còn gọi là: Proin, Propalin, Cystolamine, Uricon, Uriflex-PT, Urilin
> **Important:** In order for this drug to be effective, it must be administered exactly as directed by your veterinarian. Missed doses will negate its effect and lead to recurrent leaking. * It may take several days for the full benefit of the drug to take place. * This medication manages incontinence but does not cure it; long-term use is typically required. * **When to call the vet:** Contact your veterinarian if your pet demonstrates ongoing changes in behavior (such as excessive panting, restlessness, pacing, or irritability), if they stop eating, or if the incontinence persists or worsens.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
Veterinary professional? See the full dosing-by-species reference on VetSheet →
What it is used for
- Urethral sphincter hypotonus
- Urethral sphincter hypotonus
- Urethral sphincter hypotonus
- Urethral sphincter hypotonus
- Urethral sphincter hypotonus
- Urethral sphincter hypotonus
- Urethral sphincter hypotonus
- Retrograde ejaculation
How it is given
Possible side effects
- Restlessness
- Anxiety
- Irritability
- Urine retention
- Tachycardia
- Hypertension
- Anorexia
- Rare reports of 'stroke' in dogs
- Panting
Cautions & contraindications
- Glaucoma
- Prostatic hypertrophy
- Hyperthyroidism
- Diabetes mellitus
- Cardiovascular disorders
- Hypertension
- Severe renal or hepatic disease
- Use with caution in patients with glaucoma, prostatic hypertrophy, hyperthyroidism, diabetes mellitus, cardiovascular disorders, or hypertension. May cause decreased ovum implantation, though clinical experience has not demonstrated untoward effects during pregnancy.
Drug interactions
- Halothane: Increased risk of arrhythmias. Propranolol may be administered should these occur.
- Monoamine Oxidase (MAO) Inhibitors (e.g., amitraz, selegiline): Should not be given within two weeks of receiving MAOIs due to risk of severe hypertension and toxicity.
- NSAIDs (including aspirin): Increased chance of hypertension if given concomitantly.
- Reserpine: Increased chance of hypertension if given concomitantly.
- Other Sympathomimetic Agents (e.g., ephedrine): Should not be administered together as increased toxicity may result.
- Tricyclic Antidepressants (e.g., clomipramine, amitriptyline): Increased chance of hypertension if given concomitantly.
- NSAIDs: Increased risk of hypertension
- Monoamine Oxidase Inhibitors (MAOIs): Risk of severe hypertensive crisis
- Tricyclic Antidepressants: Increased sympathomimetic effects and risk of hypertension
Câu hỏi thường gặp
What is Phenylpropanolamine used for in pets?
> Important: In order for this drug to be effective, it must be administered exactly as directed by your veterinarian. Missed doses will negate its effect and lead to recurrent leaking. • It may take several days for the full benefit of the drug to take place. • This medication manages incontinence but does not cure it; long-term use is typically required. • When to call the vet: Contact your veterinarian if your pet demonstrates ongoing changes in behavior (such as excessive panting, restlessness, pacing, or irritability), if they stop eating, or if the incontinence persists or worsens.
Is Phenylpropanolamine safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
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