Xylitol Toxicity
Juga dikenali sebagai: Xylitol ingestion, Xylitol poisoning
Ringkasnya
Xylitol toxicity is a life-threatening emergency in dogs caused by the ingestion of a common sugar substitute. It triggers a massive release of insulin, leading to dangerously low blood sugar (hypoglycemia) and potentially devastating liver damage. Immediate veterinary intervention is critical for survival.
TL;DR. Xylitol menyebabkan hipoglisemia pantas dan mungkin nekrosis hati; keutamaan tertinggi.
Banyak produk tanpa gula seperti gula-gula getah mengandungi xylitol toksik.
Apakah itu?
Pankreas anjing melepaskan insulin secara besar-besaran akibat xylitol, menyebabkan hipoglisemia. Dos lebih tinggi: nekrosis hati akut.
"Certain toxins have been associated with hypoglycemia in dogs and cats... These drugs are thought to stimulate insulin secretion from the pancreas..."
Pada anjing xylitol mendorong pelepasan insulin dan boleh merosakkan hati.
Punca dan faktor risiko
Gula-gula getah dan mint tanpa gula; sesetengah mentega kacang; kuih tanpa gula; ubat gigi; vitamin kunyah; sesetengah ubat cecair manusia. Tiada predisposisi baka; anjing kecil risiko lebih tinggi.
Tanda
- Hipoglisemia (kardinal)
- Ataksia, kelemahan, fasikulasi, sawan, rebah
- Kegelisahan; nekrosis/kegagalan hati sering selepas 24–48 j
Ataksia dan kelemahan ialah tanda awal.
Diagnosis
Sejarah pendedahan dan tanda. Glukosa segera dan bersiri. Enzim hati baseline dan bersiri 24–72 j.
Rawatan
Tiada antidot kimia khusus. Emesis hanya jika sangat baru dan tanpa simptom. Arang terikat lemah. Dekstrosa IV bolus + CRI; SAMe dan Acetylcysteine jika risiko hati.
Pengukuran glukosa kerap adalah penting.
Prognosis
Cemerlang dengan dos rendah dan rawatan awal. Berhati-hati hingga buruk dengan nekrosis hati.
Pencegahan
Baca label; simpan gula-gula getah; ubat gigi anjing sahaja; semak mentega kacang.
Bila hubungi veterinar
Kecemasan tahap 5. Sebarang syak: hubungi sekarang. Bawa bungkusan.
Sumber
- Small Animal Critical Care Medicine, 2nd Edition, pages 395, 431, 433.
- Plumb's Veterinary Drug Handbook, page 1622.
My highlights & notes
Tanda & simptom
Cara didiagnosis
- Blood glucose measurement
- Routine monitoring of liver enzymes
Pendekatan rawatan
Rawatan mesti dipreskripsikan doktor haiwan berlesen. Dos khusus sengaja tidak dipaparkan.
Soalan lazim
What is Xylitol Toxicity?
Xylitol toxicity is a life-threatening emergency in dogs caused by the ingestion of a common sugar substitute. It triggers a massive release of insulin, leading to dangerously low blood sugar (hypoglycemia) and potentially devastating liver damage. Immediate veterinary intervention is critical for survival.
What are the symptoms of Xylitol Toxicity?
Hypoglycemia、Ataxia (wobbly, unsteady walking)、Hepatic failure、Hepatic necrosis、Hunger、Muscle fasciculations、Nervousness、Restlessness
How is Xylitol Toxicity diagnosed?
Blood glucose measurement、Routine monitoring of liver enzymes
How is Xylitol Toxicity treated?
Rawatan mesti dipreskripsikan doktor haiwan berlesen. Dos khusus sengaja tidak dipaparkan.
Sumber
- Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 431
- Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 395
- Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 433
- Plumb · p. 1622
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