숙사메토늄

투여 방법

가능한 부작용

• Muscle fasciculations
• Hyperkalemia
• Bradycardia or arrhythmias
• Malignant hyperthermia
• Increased intraocular pressure
• Increased intragastric pressure
• Prolonged apnea

주의사항 및 금기

• Patients with pre-existing hyperkalemia
• Glaucoma or penetrating eye injuries
• Severe liver disease
• Patients with known atypical plasma pseudocholinesterase
• Conscious patients (must be fully anesthetized)
• > **Requires mechanical ventilation**. Do not use without the immediate ability to intubate and ventilate the patient. > **No analgesic properties**: Does not provide analgesia or sedation; ensure adequate depth of anesthesia before administration. > **Hyperkalemia risk**: Use with extreme caution in patients with extensive tissue trauma, burns, or upper motor neuron lesions due to the risk of severe hyperkalemia.

약물 상호작용

• Organophosphates: Inhibit pseudocholinesterase, leading to significantly prolonged neuromuscular blockade
• Carbamates: Inhibit pseudocholinesterase, leading to significantly prolonged neuromuscular blockade
• Aminoglycosides: May enhance or prolong neuromuscular blockade
• Volatile anesthetics: Enhanced neuromuscular blockade and increased risk of malignant hyperthermia

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