셀레길린

용도

• Behavioural disorders and cognitive dysfunction
• Cognitive decline in older cats

투여 방법

가능한 부작용

• No specific adverse reactions are listed in the monograph
• Clinical Pearl: May occasionally cause mild gastrointestinal upset, restlessness, or lethargy

주의사항 및 금기

• Known sensitivity to selegiline
• Lactating bitches (acts on prolactin secretion)
• Pregnant bitches
• Normal safety and handling precautions should be observed. > **Warning:** Do not use in pregnant or lactating bitches due to its effects on prolactin secretion. Strict washout periods are required when switching to or from other psychoactive medications (e.g., TCAs, SSRIs).

약물 상호작용

• Alpha-2 antagonists: Should not be administered concurrently or within 24 hours before/after use
• Pethidine: Contraindicated concurrent use
• Ephedrine: Contraindicated concurrent use
• Amitraz: Potential MAOI interaction; contraindicated
• Phenothiazines: Contraindicated concurrent use
• Morphine: Potentiates the effect of morphine
• Metronidazole: Potential interaction exists
• Prednisolone: Potential interaction exists
• Trimethoprim: Potential interaction exists
• Tricyclic antidepressants (amitriptyline, doxepin, clomipramine): Do not use selegiline for at least 2-3 weeks after TCA use
• Fluoxetine: Do not use selegiline for at least 6 weeks after long-term fluoxetine use

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