메로페넴

용도

• Pharmacokinetic data
• Bacteremia/sepsis
• UTI
• CNS infections
• Systemic infections
• Urinary tract infections
• Susceptible infections
• Susceptible infections
• Bacteremia/sepsis
• UTI
• CNS infections
• Systemic infections
• Urinary tract infections
• Susceptible infections (Small dogs)

투여 방법

가능한 부작용

• Slight hair loss over SC injection sites
• Nausea (reported in humans)
• Vomiting (reported in humans)
• Diarrhea (reported in humans)

주의사항 및 금기

• Hypersensitivity to meropenem or other carbapenems
• History of anaphylaxis after receiving any beta-lactam antibiotic
• **Warnings and Precautions:** * **Antimicrobial Stewardship:** Use should be limited or avoided unless absolutely necessary to prevent the development of resistant bacterial strains that might infect humans. * **Hypersensitivity:** Use with caution in patients with known allergies to penicillins or cephalosporins due to potential cross-reactivity. * **Pregnancy/Lactation:** FDA Category B in humans (likely safe). It is considered likely safe to use during lactation. * **Renal Impairment:** While safer than aminoglycosides, dosage adjustments (e.g., extending the dosing interval) may be necessary in severe renal failure (e.g., serum creatinine > 4 mg/dL).

약물 상호작용

• Aminoglycosides: In vitro evidence of synergy against Pseudomonas aeruginosa
• Probenecid: May increase serum concentrations and elimination half-life of meropenem

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