겜피브로질

용도

• Hypertriglyceridemia (not controlled with diet alone)
• Hypertriglyceridemia (not controlled with diet alone)
• Hypertriglyceridemia (not controlled with diet alone)
• Hypertriglyceridemia (not controlled with diet alone)

투여 방법

가능한 부작용

• Abdominal pain
• Vomiting
• Diarrhea
• Abnormal liver function tests
• Dyspepsia (human)
• CNS effects: headache, somnolence, dizziness (human)
• Myositis (human)
• Bone marrow depression (rare, human)

주의사항 및 금기

• Severe hepatic dysfunction
• Severe renal dysfunction
• Known hypersensitivity to gemfibrozil
• Use with extreme caution in dogs or cats as very limited safety data is available for this medication. > **Pregnancy Warning:** In humans, it is FDA Category C. Animal studies (rats/rabbits) have shown decreased fertility rates, decreased litter sizes, and skeletal abnormalities at doses near the human dose. Safe use during nursing cannot be assured.

약물 상호작용

• Thiazide diuretics: May possibly increase triglyceride concentrations
• Beta-blockers: May possibly increase triglyceride concentrations
• Estrogens: May possibly increase triglyceride concentrations
• Ursodiol: May reduce effectiveness of gemfibrozil
• Warfarin: Gemfibrozil may potentiate anticoagulant effects

자주 묻는 질문