시프로헵타딘

용도

• As an appetite stimulant
• As an appetite stimulant
• As an appetite stimulant
• As an appetite stimulant
• As an appetite stimulant in cats with renal insufficiency
• As an antihistamine/antipruritic
• As an antihistamine/antipruritic
• For feline asthma
• For adjunctive treatment of serotonin syndrome
• Management of allergic disease / Appetite stimulation / Aortic thromboembolism
• For photic head shaking
• For photic head shaking
• For treatment of equine Cushing's

투여 방법

가능한 부작용

• Sedation / CNS depression
• Paradoxical hyperexcitability or agitation (especially in cats)
• Anticholinergic effects (dry mucous membranes, urinary retention, tachycardia)
• Hemolytic anemia in cats (rare)
• Polyphagia (in dogs at higher doses)
• Mild depression, anorexia, or lethargy (in horses)
• Mild sedation
• Polyphagia
• Weight gain
• Reduced seizure threshold

주의사항 및 금기

• Hypersensitivity to cyproheptadine
• Prostatic hypertrophy
• Bladder neck obstruction
• Severe cardiac failure
• Angle-closure glaucoma
• Pyeloduodenal obstruction
• Urinary retention (relative)
• Angle-closure glaucoma (relative)
• Pyloroduodenal obstruction (relative)
• Use with caution in patients with conditions exacerbated by anticholinergic effects (e.g., glaucoma, urinary retention, GI stasis). **Laboratory Considerations:** * **Allergy Testing:** Antihistamines decrease the wheal and flare response. Discontinue 3-7 days prior to intradermal skin testing. * **Endocrine Testing:** May increase amylase and prolactin serum levels when administered with thyrotropin-releasing hormone (TRH).

약물 상호작용

• CNS Depressants (barbiturates, tranquilizers, etc.): Additive CNS depression
• SSRIs (sertraline, fluoxetine, paroxetine, etc.): Cyproheptadine may decrease the efficacy of the SSRI due to its serotonin antagonist properties

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