카베르골린

용도

• Estrus induction
• Estrus induction
• Estrus induction
• Pseudocyesis (pseudopregnancy)
• Pseudocyesis
• Pseudocyesis
• Adjunctive treatment of mastitis after puppies weaned
• Pre-treat mammary tumors prior to surgery (during diestrous period)
• Pregnancy termination
• Pregnancy termination
• Pituitary-dependent hyperadrenocorticism (Cushing's Disease)
• Pseudopregnancy / Suppression of lactation
• Estrus induction

투여 방법

가능한 부작용

• Vomiting (infrequent, alleviated by food)
• Coat color changes (in dogs treated >14 days)
• Postural hypotension (reported in humans)
• Dizziness (reported in humans)
• Headache (reported in humans)
• Nausea (reported in humans)

주의사항 및 금기

• Pregnancy (unless abortion is desired)
• Hypersensitivity to ergot derivatives
• Uncontrolled hypertension (in humans)
• Nursing mothers
• > **Warning:** Will cause spontaneous abortion in pregnant animals. Do not use unless pregnancy termination is the specific goal. * **Hepatic Impairment:** Patients with significantly impaired liver function should receive the drug with caution, and possibly at a lower dosage. * **Estrus Induction:** When using to induce estrus, it is recommended to wait at least 4 months after the prior cycle to allow the uterus to recover. * **Nursing:** Because cabergoline suppresses prolactin, it should not be used in nursing mothers.

약물 상호작용

• Hypotensive Drugs: Concomitant use may cause additive hypotension due to cabergoline's hypotensive effects.
• Metoclopramide: Use with cabergoline may reduce the efficacy of both drugs and should be avoided.
• Phenothiazines (e.g., acepromazine, chlorpromazine): Use of cabergoline with dopamine (D2) antagonists may reduce the efficacy of both drugs and should be avoided.
• Domperidone: Antagonizes the therapeutic effect of cabergoline
• Phenothiazines (e.g., Acepromazine): May antagonize cabergoline effects due to dopamine receptor blockade
• Hypotensive agents: Additive hypotensive effects

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