Niacinamide
Juga dikenal sebagai: Vitamin B3, Vitamin PP, Niacinamide
- **Give exactly as directed:** This medication is usually given alongside an antibiotic (like tetracycline or doxycycline) to treat immune-mediated skin conditions. - **Be patient:** It often takes **6 to 8 weeks** (sometimes up to 2 months) to see noticeable improvement in your dog's skin. - **Watch for side effects:** Contact your veterinarian if your dog experiences vomiting, loss of appetite, or unusual tiredness. - **Do not substitute:** Ensure you are using *niacinamide* (or nicotinamide) and NOT *niacin* (nicotinic acid), as niacin can cause uncomfortable flushing and other side effects. - Do not stop the medication abruptly once the skin looks better; your veterinarian will likely provide a tapering schedule.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
Veterinary professional? See the full dosing-by-species reference on VetSheet →
What it is used for
- Discoid lupus erythematosus
- Discoid lupus erythematosus or pemphigus
- Various immune-mediated diseases (DLE, pemphigus, vasculitis, dermatomyositis, etc.)
- Pemphigus foliaceous
- Adjunctive therapy for pemphigus or discoid lupus erythematosus
- Immunomodulation (e.g., lupoid onychodystrophy, discoid lupus erythematosus, pemphigus foliaceus)
How it is given
Possible side effects
- Anorexia
- Vomiting
- Lethargy
- Elevated liver enzymes (occasional)
- Increased seizure frequency (anecdotal)
- Mild gastrointestinal irritation (anorexia, vomiting, diarrhea)
Cautions & contraindications
- Liver disease
- Active peptic ulcers
- Hypersensitivity to niacinamide
- Do not use nicotinic acid (niacin) as a substitute due to severe vasodilation (flushing) effects.
- Use with caution in dogs with a history of seizures. While niacinamide alone is generally considered safe in pregnant and lactating animals, its common concurrent use with tetracycline may not be safe during pregnancy/nursing.
Drug interactions
- Insulin: May require dosage adjustments after initiating niacinamide therapy due to potential alterations in glycemic control.
- Oral Antidiabetic Agents: May require dosage adjustments after initiating niacinamide therapy.
Pertanyaan umum
What is Niacinamide used for in pets?
- Give exactly as directed: This medication is usually given alongside an antibiotic (like tetracycline or doxycycline) to treat immune-mediated skin conditions. - Be patient: It often takes 6 to 8 weeks (sometimes up to 2 months) to see noticeable improvement in your dog's skin. - Watch for side effects: Contact your veterinarian if your dog experiences vomiting, loss of appetite, or unusual tiredness. - Do not substitute: Ensure you are using *niacinamide* (or nicotinamide) and NOT *niacin* (nicotinic acid), as niacin can cause uncomfortable flushing and other side effects. - Do not stop the medication abruptly once the skin looks better; your veterinarian will likely provide a tapering schedule.
Is Niacinamide safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
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