Epizootic Catarrhal Enteritis: The Green Slime Disease
Epizootic catarrhal enteritis, nicknamed green slime disease, is a contagious viral gut illness of ferrets. This article explains the classic bright-green mucousy diarrhoea, why it spreads so fast between ferrets, the warning signs, how vets support recovery, and the hygiene steps that protect your other pets.

Quick answer
Epizootic catarrhal enteritis (ECE) is a contagious viral disease of the ferret gut, famous for bright green, mucousy diarrhoea, which is why it is called green slime disease. It spreads rapidly between ferrets by contact. It can be serious, especially in older or weak ferrets, so any ferret with green diarrhoea, that stops eating, or that is losing weight needs a ferret-savvy vet.
Epizootic catarrhal enteritis, nicknamed green slime disease, is a contagious viral gut illness of ferrets.
What ECE is
ECE is caused by a coronavirus that infects the lining of the ferret's small intestine, damaging the cells that absorb nutrients. This leads to profuse diarrhoea and poor nutrient absorption. Newly introduced ferrets, especially from shelters or shows, often bring the virus in, and it can sweep through a household. Adult ferrets exposed for the first time tend to be hit hardest, while some carriers show few signs yet still infect others.
Signs to watch for
The hallmark is sudden bright green, slimy, mucous-coated diarrhoea, sometimes with visible grainy or seedy material from undigested food. Affected ferrets may vomit, go off their food, become lethargic, and lose weight quickly. Because the damaged gut cannot absorb food well, dehydration and weight loss are the biggest dangers, particularly in older ferrets.
Why you must not wait
A ferret that stops eating can decline within hours, and ongoing diarrhoea quickly causes dehydration. ECE itself can also resemble other serious problems, including a gut blockage, which is an emergency. Because you cannot tell these apart at home, green diarrhoea or a ferret that will not eat always warrants a prompt vet visit rather than watching and waiting.
How vets help recovery
There is no instant cure for the virus, so care is supportive while the gut heals. A vet may give fluids for dehydration, medicines to protect the gut and control secondary infection, and crucially a plan for frequent feeding of an easily digested, soupy meat-based recovery diet. Keeping calories going in is often the difference between recovery and decline. Many ferrets recover with good nursing, though some older ferrets have lingering digestive trouble.

During recovery, ferrets often need frequent soupy meat-based feeds to prevent dangerous weight loss.
Protecting your other ferrets
ECE spreads easily on hands, bedding, bowls and shared spaces. Isolate any sick or newly arrived ferret, ideally in a separate room, and always handle healthy ferrets first, then the sick one. Wash hands thoroughly and change or wash clothing between them. Disinfect bowls, litter trays and surfaces, and launder bedding on a hot wash. Quarantine any new ferret for a couple of weeks before introductions.

ECE spreads by contact; quarantine new ferrets and wash hands to protect your resident ferrets.
Quick FAQs
Is ECE contagious to my other pets or to me? ECE is a ferret coronavirus and is not known to infect people, dogs or cats. It spreads readily between ferrets, so isolate affected ferrets from other ferrets.
Can ferrets recover from ECE? Many do with prompt supportive care, fluids and diligent feeding. Older or already weak ferrets are more at risk and some have long-term digestive sensitivity.
How long is a ferret infectious? A recovered ferret can shed the virus and infect others for a prolonged period, sometimes months, so ongoing hygiene and careful quarantine of new ferrets matter.
How can I prevent ECE? There is no vaccine. Prevention relies on quarantining new ferrets, good hygiene, and avoiding contact with unknown ferrets at shows or shared spaces.