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Sodium Thiosulfate

Drug class: Antidote

Sodium thiosulfate is typically administered in a **hospital setting** for emergency treatment of poisoning (like cyanide or arsenic) or to treat tissue damage from chemotherapy leaks. * If your pet receives this medication orally, it may cause **profuse diarrhea**. * Ensure your pet has access to plenty of fresh water if diarrhea occurs, and follow your veterinarian's instructions closely.

Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.

Veterinary professional? See the full dosing-by-species reference on VetSheet →

What it is used for

  • Copper poisoning
  • Cyanide toxicity secondary to cyanogenic plants
  • Arsenic poisoning
  • Copper poisoning
  • Cyanide toxicity secondary to cyanogenic plants
  • Arsenic poisoning
  • Cyanide toxicity
  • Doxorubicin extravasation
  • Carboplatin extravasation
  • Cisplatin extravasation
  • Copper poisoning
  • Cyanide toxicity secondary to cyanogenic plants
  • Arsenic poisoning
  • Cyanide toxicity
  • Cyanide toxicity
  • Arsenic toxicity
  • Cyanide toxicity
  • Doxorubicin extravasation
  • Carboplatin extravasation
  • Cisplatin extravasation

How it is given

IVPOSCTopical

Possible side effects

  • Profuse diarrhea (with large oral doses)

Cautions & contraindications

  • None absolute
  • There are no absolute contraindications. Injectable forms should be given slowly IV. Safe use during pregnancy has not been established (FDA Category C); use when benefits outweigh potential risks.

Drug interactions

  • Cyanocobalamin: Not compatible when mixed together

Frequently asked questions

What is Sodium Thiosulfate used for in pets?

Sodium thiosulfate is typically administered in a hospital setting for emergency treatment of poisoning (like cyanide or arsenic) or to treat tissue damage from chemotherapy leaks. • If your pet receives this medication orally, it may cause profuse diarrhea. • Ensure your pet has access to plenty of fresh water if diarrhea occurs, and follow your veterinarian's instructions closely.

Is Sodium Thiosulfate safe for my pet?

Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.

This article is for general education and is not a substitute for professional veterinary advice. If your pet is unwell, please consult a veterinarian.

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